Platelets are the main players in thrombotic diseases, where activated platelets not only
mediate thrombus formation but also are involved in multiple interactions with vascular cells …

Platelets store a plethora of different molecules within their granules, modulating numerous
pathways, not only in coagulation, but also in angiogenesis, wound healing, and …

Platelets play a major role in primary hemostasis and thrombus formation. After vascular
injury, platelets adhere to injured site and rapidly change their shape that switches the …

More than 130 years ago, it was recognized that platelets are key mediators of hemostasis.
Nowadays, it is established that platelets participate in additional physiological processes …

Beyond hemostasis and thrombosis, an increasing number of studies indicate that platelets
play an integral role in intercellular communication, mediating inflammatory and …

Platelets play a pivotal role in primary hemostasis where their rapid response to vascular
injury prevents excessive bleeding. To accomplish this, platelets are enriched in membrane …

Coronary atherosclerosis progression is an active process involving complex interactions
between inflammation, thrombosis and endothelial damage/dysfunction. Vascular intimal …

The most convincing evidence for the participation of platelets in arterial thrombosis in
humans comes from studies of platelet activation in patients with acute coronary syndromes …

In recent years, platelet proteomics has been applied successfully to the study of
cardiovascular diseases (CVDs). It is very well known that platelets play a pivotal role in the …

Platelets are small blood cells that adhere to the site of vessel injury where von Willebrand
factor (VWF) is expressed. Platelets bind to VWF through interaction with a membrane …