Background Deprescribing, the process of reducing or discontinuing unnecessary or harmful
medicines is an essential part of clinical practice. Objective To evaluate the efficacy of …

In response to the overuse of prescription opioid analgesics, clinical practice guidelines
encourage opioid deprescribing (ie, dose reduction or cessation) in patients with chronic …

Background This is the first update of the original Cochrane Review published in 2013. The
conclusions of this review have not changed from the 2013 publication. People with chronic …

Objective To review interventions to reduce long term opioid treatment in people with
chronic non-cancer pain, considering efficacy on dose reduction and discontinuation, pain …

Background General practitioners'(GPs) views about deprescribing prescription opioid
analgesics (POAs) may influence the care provided for patients experiencing chronic …

Opioids are regularly administered in acute and cancer pain. In chronic non‐cancer pain
(CNCP), however, their use is controversial. Previous meta‐analyses and randomized …

Background Patients with chronic non‐cancer pain who are prescribed and are taking
opioids can have a history of long term high dose opioid use without effective pain relief. In …

Background Opioids are prescribed frequently and increasingly for the management of
chronic non-cancer pain (CNCP). Current systematic reviews have a number of limitations …

Long‐term opioid management for chronic noncancer pain - Noble, M - 2010 | Cochrane
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Background Deprescribing (reduction or cessation) of prescribed opioids can be
challenging for both patients and healthcare professionals. Objective To synthesize and …