Iron status and restless legs syndrome in the elderly

ST O'keeffe, K Gavin, JN Lavan - Age and ageing, 1994 - academic.oup.com
The relationship between iron status and the restless legs syndrome (RLS) was examined in
18 elderly patients with RLS and in 18 matched control subjects. A rating scale with a …

Iron metabolism and the risk of restless legs syndrome in an elderly general population–the MEMO-Study

K Berger, A von Eckardstein, C Trenkwalder… - Journal of …, 2002 - Springer
Background: Low iron and ferritin blood levels have been observed in patients with Restless
Legs Syndrome (RLS) with an inverse relation between symptom severity and ferritin level …

Iron and the restless legs syndrome

ER Sun, CA Chen, G Ho, CJ Earley, RP Allen - Sleep, 1998 - academic.oup.com
Study Objectives: Using blinded procedures, determine the relation between serum ferritin
levels and severity of subjective and objective symptoms of the restless legs syndrome …

Efficacy of oral iron in patients with restless legs syndrome and a low-normal ferritin: a randomized, double-blind, placebo-controlled study

J Wang, B O'Reilly, R Venkataraman, V Mysliwiec… - Sleep medicine, 2009 - Elsevier
BACKGROUND AND PURPOSE: Restless Legs Syndrome (RLS) is a primary disorder of
sensation that affects sleep and has been associated with iron deficiency. The purpose of …

Low body stores of iron and restless legs syndrome: a correctable cause of insomnia in adolescents and teenagers

MH Kryger, K Otake, J Foerster - Sleep Medicine, 2002 - Elsevier
Background: It has been shown that restless legs syndrome (RLS) in adults may be linked to
abnormalities in iron stores. Whether reduced iron stores play a role in children is not clear …

Ferritin subunits in CSF are decreased in restless legs syndrome

SL Clardy, CJ Earley, RP Allen, JL Beard… - Journal of Laboratory and …, 2006 - Elsevier
Restless legs syndrome (RLS) is a neurological disorder that may be related to iron
misregulation at the level of the central nervous system. Evidence that iron is involved in …

CSF iron, ferritin and transferrin levels in restless legs syndrome

S Mizuno, T Mihara, T Miyaoka, T Inagaki… - Journal of sleep …, 2005 - Wiley Online Library
The aim of this study is evaluating iron, ferritin, and transferrin in both serum and CSF in
patients of restless legs syndrome (RLS), based on the hypothesis that iron deficiency in the …

Ferritin levels in the cerebrospinal fluid and restless legs syndrome: effects of different clinical phenotypes

CJ Earley, JR Connor, JL Beard, SL Clardy, RP Allen - Sleep, 2005 - academic.oup.com
Abstract Study Objective: To determine whether patients with restless legs syndrome (RLS)
and controls differ in regard to levels of ferritin and transferrin in the cerebrospinal fluid …

Repeated IV doses of iron provides effective supplemental treatment of restless legs syndrome

CJ Earley, D Heckler, RP Allen - Sleep medicine, 2005 - Elsevier
BACKGROUND AND PURPOSE: To evaluate in RLS patients the efficacy and safety of
repeated infusions of iron in order to maintain symptomatic improvements achieved with a …

Restless legs syndrome in blood donors

J Ulfberg, B Nyström - Sleep medicine, 2004 - Elsevier
BACKGROUND AND PURPOSE: Restless legs syndrome (RLS) may be a cause of
significant sleep disturbance. In a Swedish survey, the prevalence of RLS has been …