Pulmonary arterial hypertension: pathogenesis and clinical management

T Thenappan, ML Ormiston, JJ Ryan, SL Archer - Bmj, 2018 - bmj.com
Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …

[HTML][HTML] Pulmonary arterial hypertension: pathophysiology and treatment

NSH Lan, BD Massam, SS Kulkarni, CC Lang - Diseases, 2018 - mdpi.com
Pulmonary arterial hypertension (PAH), the first category of pulmonary hypertension, is a
chronic and progressive disorder characterised by angioproliferative vasculopathy in the …

Epidemiology and treatment of pulmonary arterial hypertension

EMT Lau, E Giannoulatou, DS Celermajer… - Nature Reviews …, 2017 - nature.com
In the past 2 decades, major changes have occurred in the epidemiological and treatment
landscape of pulmonary arterial hypertension (PAH). Previously regarded as a disease of …

Challenges in the diagnosis and treatment of pulmonary arterial hypertension

JL Vachiéry, S Gaine - European respiratory review, 2012 - Eur Respiratory Soc
Advances in the diagnosis and management of pulmonary arterial hypertension (PAH) have
resulted in significant improvements in outcomes for patients with this devastating and …

[HTML][HTML] Current and emerging therapeutic approaches to pulmonary hypertension

M Bisserier, N Pradhan, L Hadri - Reviews in cardiovascular …, 2020 - ncbi.nlm.nih.gov
Pulmonary arterial hypertension (PAH) is a progressive and fatal lung disease of
multifactorial etiology. Most of the available drugs and FDA-approved therapies for treating …

Evidence-based pharmacologic management of pulmonary arterial hypertension

N Benedict, A Seybert, MA Mathier - Clinical therapeutics, 2007 - Elsevier
Background: Pulmonary arterial hypertension (PAH) is a debilitating chronic disorder of the
pulmonary vasculature characterized by elevated mean pulmonary arterial pressure, right …

Clinical trial design and new therapies for pulmonary arterial hypertension

O Sitbon, M Gomberg-Maitland… - European …, 2019 - Eur Respiratory Soc
Until 20 years ago the treatment of pulmonary arterial hypertension (PAH) was based on
case reports and small series, and was largely ineffectual. As a deeper understanding of the …

[HTML][HTML] Management of pulmonary arterial hypertension

JD Mayeux, IZ Pan, J Dechand, JA Jacobs… - Current cardiovascular …, 2021 - Springer
Abstract Purpose of Review This review focuses on the therapeutic management and
individualized approach to Group 1 pulmonary arterial hypertension (PAH), utilizing Food …

Pulmonary arterial hypertension: epidemiology and registries

MD McGoon, RL Benza, P Escribano-Subias… - Journal of the American …, 2013 - jacc.org
Registries of patients with pulmonary arterial hypertension (PAH) have been instrumental in
characterizing the presentation and natural history of the disease and provide a basis for …

[HTML][HTML] Pulmonary arterial hypertension

D Montani, S Günther, P Dorfmüller, F Perros… - Orphanet journal of rare …, 2013 - Springer
Pulmonary arterial hypertension (PAH) is a chronic and progressive disease leading to right
heart failure and ultimately death if untreated. The first classification of PH was proposed in …