[HTML][HTML] Selenium-incorporated mesoporous silica nanoparticles for osteosarcoma therapy

L He, P Habibovic, S van Rijt - Biomaterials Science, 2023 - pubs.rsc.org
Selenium (Se) compounds are promising chemotherapeutics due to their ability to inhibit
cancer cell activity via the generation of reactive oxygen species (ROS). However, to …

ROS/GSH dual-responsive selenium-containing mesoporous silica nanoparticles for drug delivery

WJ Zhang, A Babu, YZ Yan, SS Park, NJ Jo… - Journal of Porous …, 2023 - Springer
The targeted delivery of anti-tumor drugs to diseased sites is significant in cancer therapy.
Herein, a novel redox-responsive 5-fluorouracil (5-FU) prodrug delivery system based on …

Redox-responsive mesoporous selenium delivery of doxorubicin targets MCF-7 cells and synergistically enhances its anti-tumor activity

S Zhao, Q Yu, J Pan, Y Zhou, C Cao, JM Ouyang, J Liu - Acta biomaterialia, 2017 - Elsevier
To reduce the side effects and enhance the anti-tumor activities of anticancer drugs in the
clinic, the use of nano mesoporous materials, with mesoporous silica (MSN) being the best …

Mesoporous selenium nanoparticles for therapeutic goals: a review

F Davarani Asl, M Mousazadeh, M Azimzadeh… - Journal of Nanoparticle …, 2022 - Springer
Nowadays, one of the main applications of nanoparticles is their usage in therapeutics and
drug delivery systems. They can be used for targeted, more efficient, and less cytotoxic drug …

Construction of Selenium Nanoparticle-Loaded Mesoporous Silica Nanoparticles with Potential Antioxidant and Antitumor Activities as a Selenium Supplement

M Wang, X Sun, Y Wang, X Deng, J Miao, D Zhao… - ACS …, 2022 - ACS Publications
Excessive reactive oxygen species (ROS) can damage cells and affect normal cell functions,
which are related to various diseases. Selenium nanoparticles are a potential selenium …

Mesoporous silica nanoparticles for tissue‐engineering applications

L Chen, X Zhou, C He - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs) have been widely investigated as a nanocarrier for
the delivery of various cargoes in nanomedicine. The application of MSNs in tissue …

Construction of selenium-embedded mesoporous silica with improved antibacterial activity

J Chen, Y Wei, X Yang, S Ni, F Hong, S Ni - Colloids and Surfaces B …, 2020 - Elsevier
In this work, different concentrations of Se-incorporated mesoporous silica nanospheres
(MSNs)(5Se/MSNs and 10Se/MSNs) were successfully synthesized via an in-situ one-pot …

[HTML][HTML] Biodegradable zinc-containing mesoporous silica nanoparticles for cancer therapy

S Chen, SL Greasley, ZY Ong… - Materials Today …, 2020 - Elsevier
Triple-negative breast cancers are extremely aggressive with limited treatment options
because of the reduced response of the cancerous cells to hormonal therapy. Here …

Selenium tethered mesoporous silica nanocomposite enhances drug delivering efficiency to target breast cancer

K Vimala, A Maruthupandian, R Thangaraj… - Journal of Cluster …, 2021 - Springer
The development of multifunctional nanocomposite can greatly improve therapeutic effects
to impair tumor proliferation. In the present study, we developed a new class of dual-drug …

[HTML][HTML] Mesoporous silica nanoparticles as drug delivery vehicles in cancer

A Watermann, J Brieger - Nanomaterials, 2017 - mdpi.com
Even though cancer treatment has improved over the recent decades, still more specific and
effective treatment concepts are mandatory. Surgical removal is not always possible …