Alcohol aggravates ketamine-induced behavioral, morphological and neurochemical alterations in adolescent rats: The involvement of CREB-related pathways
D Zuo, Y Liu, Z Liu, J Cui, X Zhou, Y Liu, Z Li… - Behavioural Brain …, 2018 - Elsevier
Currently, an increasing proportion of adolescent ketamine users simultaneously consume
alcohol. However, the potential behavioural and neurological alterations induced by such a …
alcohol. However, the potential behavioural and neurological alterations induced by such a …
The effects of sub-anesthetic ketamine plus ethanol on behaviors and apoptosis in the prefrontal cortex and hippocampus of adolescent rats
Ketamine has become increasingly popular in adolescent drug abusers worldwide.
Meanwhile, alcohol is usually used by ketamine users. However, little work has been …
Meanwhile, alcohol is usually used by ketamine users. However, little work has been …
The interactive effects of ketamine and ethanol on dopamine expression in the ventral tegmental area of rats
ZB Zhang, TY Xu, DY You, S Yi, Q Liu… - Neuropsychiatric …, 2018 - Taylor & Francis
Background A number of studies have demonstrated the significant and rapid
antidepressant effects of ketamine, which is also known as a neurotoxic and illicit drug …
antidepressant effects of ketamine, which is also known as a neurotoxic and illicit drug …
[HTML][HTML] Alcohol amplifies ketamine-induced apoptosis in primary cultured cortical neurons and PC12 cells through down-regulating CREB-related signaling pathways
D Zuo, F Sun, J Cui, Y Liu, Z Liu, X Zhou, Z Li, Y Wu - Scientific Reports, 2017 - nature.com
Recreational use of ketamine (KET) has been increasing worldwide. Previous studies have
demonstrated that KET induced neurotoxicity; however, few studies have examined how …
demonstrated that KET induced neurotoxicity; however, few studies have examined how …
[HTML][HTML] One binge-type cycle of alcohol plus ketamine exposure induces emotional-like disorders associated with oxidative damage in adolescent female rats
CCM da Silveira, S de Carvalho Cartágenes… - Biomedicine & …, 2023 - Elsevier
Drug abuse is a global public health problem among adolescents, with alcohol often used in
association with other psychotropic drugs, such as ketamine. Considering the scarcity of …
association with other psychotropic drugs, such as ketamine. Considering the scarcity of …
Subchronic ketamine alters behaviour, metabolic indices and brain morphology in adolescent rats: Involvement of oxidative stress, glutamate toxicity and caspase-3 …
AY Onaolapo, OJ Ayeni, MO Ogundeji, A Ajao… - Journal of chemical …, 2019 - Elsevier
Ketamine is a dissociative anaesthetic agent whose recreational use amongst adolescents
and young adults is reaching epidemic proportions in a number of countries. While animal …
and young adults is reaching epidemic proportions in a number of countries. While animal …
Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains
CR Majewski-Tiedeken, CR Rabin, SJ Siegel - Drug and alcohol …, 2008 - Elsevier
BACKGROUND: Drug abuse is common among adolescents and young adults. Although
the consequences of intoxication are known, sequelae of drugs emerging on campuses and …
the consequences of intoxication are known, sequelae of drugs emerging on campuses and …
Juvenile exposure to ketamine causes delayed emergence of EEG abnormalities during adulthood in mice
RE Featherstone, LR Nagy, CG Hahn… - Drug and alcohol …, 2014 - Elsevier
Background Increased susceptibility to cognitive impairment or psychosis in adulthood is
associated with adolescent drug abuse. Studies in adults have identified impairments in …
associated with adolescent drug abuse. Studies in adults have identified impairments in …
[HTML][HTML] Neuropsychological Assessment of Learning and Memory in Rats Following Ketamine Exposure during Late Adolescence
JM Davis, D Compton, M Heit, A Fravel… - Journal of Behavioral and …, 2020 - scirp.org
With the prevalent issue of drug abuse in society, research regarding the effects of ketamine,
a drug frequently abused by youth in club settings, has increased. Despite its potential for …
a drug frequently abused by youth in club settings, has increased. Despite its potential for …
Chronic ketamine exposure induces permanent impairment of brain functions in adolescent cynomolgus monkeys
L Sun, Q Li, Q Li, Y Zhang, D Liu, H Jiang… - Addiction …, 2014 - Wiley Online Library
Ketamine, a non‐competitive N‐methyl‐D‐aspartic acid receptor antagonist, has emerged
as an increasingly popular drug among young drug abusers worldwide. Available evidence …
as an increasingly popular drug among young drug abusers worldwide. Available evidence …