Enriched tumor epithelium, tumor-associated stroma, and whole tissue were collected by
laser microdissection from thin sections across spatially separated levels of ten high-grade …

Background Although uterine serous carcinoma (USC) represents a small proportion of all
uterine cancer cases, patients with this aggressive subtype typically have high rates of …

Multiple studies have identified transcriptome subtypes of high-grade serous ovarian
carcinoma (HGSOC), but their interpretation and translation are complicated by tumor …

Bulk and single-cell RNA sequencing do not provide full characterization of tissue spatial
diversity in cancer samples, and currently available in situ techniques (multiplex …

Clear cell carcinoma (CCC), endometrioid carcinoma (EC), and serous carcinoma (SC) are
the major histological subtypes of epithelial ovarian cancer (EOC), whose differences in …

Simple Summary High-grade serous ovarian cancer (HGSC) caused more than 13,000
deaths annually in the United States. A critically important component that influences the …

Background/Aim: Ovarian cancer (OVCA) is characterized by genomic/molecular intra-
patient heterogeneity (IPH). Tissue histology and morphological features are surrogates of …

Ovarian serous carcinomas (OSCs) comprise over half of all ovarian carcinomas and
account for the majority of ovarian cancer-related deaths. We used a 2-dimensional liquid …

Purpose To identify proteins and (molecular/biological) pathways associated with
differences between benign and malignant epithelial ovarian tumors. Experimental …

Ovarian cancer, the second most common gynecological malignancy, accounts for 3% of all
cancers among women in the United States, and has a high mortality rate, largely because …