Monocytes are innate blood cells that maintain vascular homeostasis and are early
responders to pathogens in acute infections. There are three well-characterized classes of …

Nonclassical patrolling monocytes are characterized by their unique ability to actively patrol
the vascular endothelium under homeostatic and inflammatory conditions. Patrolling …

Classical and non-classical monocytes are two well-defined subsets of monocytes
displaying distinct roles. They differentially express numerous genes relevant to their …

Monocytes participate importantly in immunity. Produced in the bone marrow and released
into the blood, they circulate in blood or reside in a spleen reservoir before entering tissue …

Monocytes express various receptors, which monitor and sense environmental changes.
Monocytes are highly plastic and heterogeneous, and change their functional phenotype in …

In a nomenclature proposal published in 2010 monocytes were subdivided into classical
and non-classical cells and in addition an intermediate monocyte subset was proposed …

Monocytes are circulating myeloid immune precursor cells that are generated in the bone
marrow. Mature monocytes are released into the circulation and, in case of need, recruited …

The role of nonclassical monocytes (NCMs) in health and disease is emerging, but their
location and function within tissues remain poorly explored. Imaging of NCMs has been …

In humans, the monocyte pool comprises three subsets (classical, intermediate, and
nonclassical) that circulate in dynamic equilibrium. The kinetics underlying their generation …

Monocytes are circulating blood leukocytes that play important roles in the inflammatory
response, which is essential for the innate response to pathogens. But inflammation and …