Synthesis and Antioxidant Activity of Some New Heterocycles Incorporating the Pyrazolo-[3,4-D]Pyrimidin-4-One Moiety
A El-Mekabaty - Chemistry of Heterocyclic Compounds, 2015 - Springer
2-(4-Oxo-1-phenyl-4, 5-dihydro-1H-pyrazolo [3, 4-d] pyrimidin-6-yl) acetonitrile was used as
the key intermediate for the synthesis of polyfunctionally substituted heterocycles (eg …
the key intermediate for the synthesis of polyfunctionally substituted heterocycles (eg …
Synthesis and Antioxidant Activity of New Pyrazolo[1,5‐a]Pyrimidine Derivatives Incorporating a Thiazol‐2‐yldiazenyl Moiety
A El‐Mekabaty, OMO Habib… - Journal of …, 2016 - Wiley Online Library
4‐(Thiazol‐2‐yldiazenyl)‐1H‐pyrazole‐3, 5‐diamine (2) was prepared by the reaction of 2‐
thiazolylazomalononitrile (1) with hydrazine hydrate in boiling ethanol and used as key …
thiazolylazomalononitrile (1) with hydrazine hydrate in boiling ethanol and used as key …
Synthesis of some new fused pyrazole derivatives bearing indole moiety as antioxidant agents
A El‐Mekabaty, HA Etman… - Journal of Heterocyclic …, 2016 - Wiley Online Library
3‐(1H‐Indol‐3‐yl)‐1H‐pyrazol‐5‐amine 3 was prepared in a quantitative yield by heating 3‐
(1H‐indol‐3‐yl)‐3‐oxopropanenitrile 2 in dry ethanol with hydrazine hydrate, and utilized as …
(1H‐indol‐3‐yl)‐3‐oxopropanenitrile 2 in dry ethanol with hydrazine hydrate, and utilized as …
Synthesis of some new functionalized pyrano[2,3-c]pyrazoles and pyrazolo[4′,3′:5,6] pyrano[2,3-d]pyrimidines bearing a chromone ring as antioxidant agents
TE Ali, DA Bakhotmah, MA Assiri - Synthetic Communications, 2020 - Taylor & Francis
A new series of functionalized pyrano [2, 3-c] pyrazoles and pyrazolo [4′, 3′: 5, 6] pyrano
[2, 3-d] pyrimidines bearing a bioactive chromone ring was achieved. The methodology …
[2, 3-d] pyrimidines bearing a bioactive chromone ring was achieved. The methodology …
Synthesis and antioxidant evaluation of some new pyrazolopyridine derivatives
MA Gouda - Archiv der Pharmazie, 2012 - Wiley Online Library
Dimethyl‐1H‐pyrazolo [3, 4‐b] pyridine‐3‐amine (1) was used as a key intermediate for the
synthesis of imidazolopyrazole derivatives 7–11 upon interaction with 3‐(2‐bromoacetyl) …
synthesis of imidazolopyrazole derivatives 7–11 upon interaction with 3‐(2‐bromoacetyl) …
Synthesis, Characterization, and Antioxidant Evaluation of Some Novel Pyrazolo[3,4‐c][1,2]diazepine and Pyrazolo[3,4‐c]pyrazole Derivatives
KS Mohammed, EE Elbeily… - Journal of …, 2019 - Wiley Online Library
5‐Hydrazineyl‐3‐methyl‐1H‐pyrazole (1) was used as a starting material for the synthesis
of novel pyrazolo [3, 4‐c][1, 2] diazepine derivatives 3, 4, and 6a, b by its reaction with …
of novel pyrazolo [3, 4‐c][1, 2] diazepine derivatives 3, 4, and 6a, b by its reaction with …
[PDF][PDF] Antioxidant activity of novel pyrimidines derived from Arylidenes
HMF Madkour, KA Kandeel, MS Salem… - International Journal of …, 2014 - Citeseer
Arylidenes have been utilized as a scaffold for synthesis of different heterocyclic compounds
such as thiazolo [3, 2-a] pyridine, pyridinium salt of pyrano [2, 3-d] pyrimidine and 2 …
such as thiazolo [3, 2-a] pyridine, pyridinium salt of pyrano [2, 3-d] pyrimidine and 2 …
Novel Pyrazolo[1,5‐a]Pyrimidines and Pyrazolo[5,1‐c][1,2,4]Triazines Incorporating Indole Moiety as a New Class of Antioxidant Agents
A El‐Mekabaty, AA Fadda - Journal of Heterocyclic Chemistry, 2018 - Wiley Online Library
This effort focuses on the construction of novel pyrazolo [1, 5‐a] pyrimidines bearing indole
nucleus via the reaction of 3‐(1H‐indol‐3‐yl)‐1H‐pyrazol‐5‐amine (3) with the appropriate …
nucleus via the reaction of 3‐(1H‐indol‐3‐yl)‐1H‐pyrazol‐5‐amine (3) with the appropriate …
Synthesis and antioxidant properties of novel pyrimidine-containing heterocycles
MS Salem, AO Errayes - Journal of Chemical Research, 2016 - journals.sagepub.com
4-(Benzo [d][1, 3] dioxol-5-yl)-2-hydrazinyl-6-oxo-1, 6-dihydropyrimidine-5-carbonitrile was
utilised to construct fused heterocyclic systems, namely triazolopyrimidines, as well as non …
utilised to construct fused heterocyclic systems, namely triazolopyrimidines, as well as non …
Synthesis and reactions of some novel nicotinonitrile, thiazolotriazole, and imidazolotriazole derivatives for antioxidant evaluation
HH Sayed, EMH Morsy, EM Flefel - Synthetic Communications®, 2010 - Taylor & Francis
The novel 2-(1 H)-pyridone, the lead compound of the pyridone derivative 1, reacted with an
electrophilic reagent (ethyl chloroacetate) to give the corresponding ester 2. Condensation …
electrophilic reagent (ethyl chloroacetate) to give the corresponding ester 2. Condensation …