Members of the tripartite motif (TRIM) protein family strongly induced by interferons (IFNs)
are parts of the innate immune system with antiviral activity. However, it is still unclear which …

Hepatitis B virus (HBV) infection represents one of the most critical health problems
worldwide. Tripartite motif protein 38 (TRIM38) is an interferon-stimulated gene (ISG) that …

Type I interferon (IFN) response is central for host defense against viral infection. Tripartite
motif 27 (TRIM27) is implicated in antiviral innate immune response; however, whether it …

Members of the tripartite motif (TRIM) family are a part of the innate immune system to
counter intracellular pathogens. TRIM22 has been reported to possess antiretroviral activity …

Tripartite motif (TRIM) proteins constitute a family of over 100 members that share conserved
tripartite motifs and exhibit diverse biological functions. Several TRIM proteins have been …

Hepatitis B virus (HBV) remains a major cause of hepatic disease that threatens human
health worldwide. Type I IFN (IFN-I) therapy is an important therapeutic option for HBV …

To understand the molecular mechanisms that mediate the anti-hepatitis B virus (HBV) effect
of interferon (IFN) therapy, we conduct high-throughput bimolecular fluorescence …

TRIM5γ, together with TRIM31, has been shown to promote HBx ubiquitination and
degradation. This study aimed to explore whether a patient with HCC (hepatic cell …

Background: The hepatitis B virus (HBV) vaccine has been efficiently used for decades.
However, hepatocellular carcinoma caused by HBV is still prevalent globally. We previously …

Chronic hepatitis B virus (HBV) infection is a major medical concern worldwide. Current
treatments for HBV infection effectively inhibit virus replication; however, these treatments …