TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity
X Tian, H Dong, X Lai, G Ou, J Cao, J Shi, C Xiang… - Antiviral Research, 2022 - Elsevier
Members of the tripartite motif (TRIM) protein family strongly induced by interferons (IFNs)
are parts of the innate immune system with antiviral activity. However, it is still unclear which …
are parts of the innate immune system with antiviral activity. However, it is still unclear which …
[HTML][HTML] The antiviral activity of tripartite motif protein 38 in hepatitis B virus replication and gene expression and its association with treatment responses during PEG …
H Luo, X Hu, Y Li, D Lei, G Tan, Y Zeng, B Qin - Virology, 2023 - Elsevier
Hepatitis B virus (HBV) infection represents one of the most critical health problems
worldwide. Tripartite motif protein 38 (TRIM38) is an interferon-stimulated gene (ISG) that …
worldwide. Tripartite motif protein 38 (TRIM38) is an interferon-stimulated gene (ISG) that …
TRIM27 promotes hepatitis C virus replication by suppressing type I interferon response
F Zheng, N Xu, Y Zhang - Inflammation, 2019 - Springer
Type I interferon (IFN) response is central for host defense against viral infection. Tripartite
motif 27 (TRIM27) is implicated in antiviral innate immune response; however, whether it …
motif 27 (TRIM27) is implicated in antiviral innate immune response; however, whether it …
[PDF][PDF] Tripartite motif‐containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear‐located RING domain
B Gao, Z Duan, W Xu, S Xiong - Hepatology, 2009 - Wiley Online Library
Members of the tripartite motif (TRIM) family are a part of the innate immune system to
counter intracellular pathogens. TRIM22 has been reported to possess antiretroviral activity …
counter intracellular pathogens. TRIM22 has been reported to possess antiretroviral activity …
Identification and characterization of multiple TRIM proteins that inhibit hepatitis B virus transcription
Tripartite motif (TRIM) proteins constitute a family of over 100 members that share conserved
tripartite motifs and exhibit diverse biological functions. Several TRIM proteins have been …
tripartite motifs and exhibit diverse biological functions. Several TRIM proteins have been …
Identification of TRIM14 as a Type I IFN-Stimulated Gene Controlling Hepatitis B Virus Replication by Targeting HBx
G Tan, F Xu, H Song, Y Yuan, Q Xiao, F Ma… - Frontiers in …, 2018 - frontiersin.org
Hepatitis B virus (HBV) remains a major cause of hepatic disease that threatens human
health worldwide. Type I IFN (IFN-I) therapy is an important therapeutic option for HBV …
health worldwide. Type I IFN (IFN-I) therapy is an important therapeutic option for HBV …
Type-I-IFN-stimulated gene TRIM5γ inhibits HBV replication by promoting HBx degradation
To understand the molecular mechanisms that mediate the anti-hepatitis B virus (HBV) effect
of interferon (IFN) therapy, we conduct high-throughput bimolecular fluorescence …
of interferon (IFN) therapy, we conduct high-throughput bimolecular fluorescence …
Type-III interferon stimulated gene TRIM31 mutation in an HBV patient blocks its ability in promoting HBx degradation
F Xu, H Song, Q Xiao, Q Wei, X Pang, Y Gao, G Tan - Virus Research, 2022 - Elsevier
TRIM5γ, together with TRIM31, has been shown to promote HBx ubiquitination and
degradation. This study aimed to explore whether a patient with HCC (hepatic cell …
degradation. This study aimed to explore whether a patient with HCC (hepatic cell …
TRIM25 inhibits HBV replication by promoting HBx degradation and the RIG-I-mediated pgRNA recognition
H Song, Q Xiao, F Xu, Q Wei, F Wang… - Chinese Medical …, 2023 - mednexus.org
Background: The hepatitis B virus (HBV) vaccine has been efficiently used for decades.
However, hepatocellular carcinoma caused by HBV is still prevalent globally. We previously …
However, hepatocellular carcinoma caused by HBV is still prevalent globally. We previously …
TRIM26 positively affects hepatitis B virus replication by inhibiting proteasome-dependent degradation of viral core protein
Y Nakaya, T Nishizawa, H Nishitsuji, H Morita… - Scientific reports, 2023 - nature.com
Chronic hepatitis B virus (HBV) infection is a major medical concern worldwide. Current
treatments for HBV infection effectively inhibit virus replication; however, these treatments …
treatments for HBV infection effectively inhibit virus replication; however, these treatments …