Background Lung cancer is the leading cause of cancer-related mortality. Radiology and
bronchoscopy techniques do not have the necessary resolution to evaluate lung lesions on …

Lung cancer is the leading cause of cancer-related deaths1. Squamous cell and small cell
cancers typically arise in association with the conducting airways, whereas …

Purpose: Current diagnostic imaging modalities for human bronchial airways do not possess
sufficient resolution and tissue penetration depth to detect early morphologic changes and to …

Transbronchial needle aspiration (TBNA) is a procedure routinely performed to diagnose
peripheral pulmonary lesions. However, TBNA is associated with a low diagnostic yield due …

Background: Full-field optical coherence tomography (FFOCT) is a real-time imaging
technique that generates high-resolution three-dimensional tomographic images from …

Background High-resolution computed tomography has limitations in the assessment of
airway wall layers and related remodeling in obstructive lung diseases. Near infrared-based …

We present the first endoscopic Doppler optical coherence tomography and co-registered
autofluorescence imaging (DOCT-AFI) of peripheral pulmonary nodules and vascular …

Lung cancer is the leading cause of cancer-related deaths in the United States and the
second most common type of cancer in both men and women. Optical coherence …

Determination of chemotherapy efficacy early during treatment would provide more
opportunities for physicians to alter and adapt treatment plans. Diffuse optical technologies …

The investigation of many lung diseases currently requires bronchoscopic or surgical
histopathological tissue biopsy. This creates risks for patients and entails processing costs …