A scoping review of recent advances in the application of comet assay to Allium cepa roots

C Alias, I Zerbini, D Feretti - Environmental and Molecular …, 2023 - Wiley Online Library
The comet assay is a sensitive method for the evaluation of DNA damages and DNA repair
capacity at single‐cell level. Allium cepa is a well‐established plant model for toxicological …

The use of comet assay in plant toxicology: recent advances

CLV Santos, B Pourrut… - Frontiers in Genetics, 2015 - frontiersin.org
The systematic study of genotoxicity in plants induced by contaminants and other stress
agents has been hindered to date by the lack of reliable and robust biomarkers. The comet …

Sensitivity of Allium and Nicotiana in cellular and acellular comet assays to assess differential genotoxicity of direct and indirect acting mutagens

A Bandyopadhyay, A Mukherjee - Ecotoxicology and environmental safety, 2011 - Elsevier
We have evaluated the extent of DNA damage induced by direct and indirect mutagens by
cellular and acellular comet assays in two plant systems, Nicotiana tabacum (wild type …

Reliability of plant root comet assay in comparison with human leukocyte comet assay for assessment environmental genotoxic agents

GB Dos Reis, LF Andrade-Vieira… - Ecotoxicology and …, 2017 - Elsevier
Comet assay is an efficient test to detect genotoxic compounds based on observation of
DNA damage. The aim of this work was to compare the results obtained from the comet …

[PDF][PDF] Review on Comet Assay: a reliable tool for assessing DNA damage in animal models

AB Andem, RB Agbor, IA Ekpo - Journal of Current Research in …, 2013 - researchgate.net
The Comet assay has found worldwide acceptance for detecting DNA damage and repair in
prokaryotic and eukaryotic cells. The variability in the results of the Comet assay is largely …

Comet assay application in environmental monitoring: DNA damage in human leukocytes and plant cells in comparison with bacterial and yeast tests

P Poli, A Buschini, FM Restivo, A Ficarelli… - …, 1999 - academic.oup.com
Urban airborne particulate is a complex mixture of air pollutants, many of which have not
been identified. However, short-term mutagenesis tests together with chemicophysical …

The comet assay: ready for 30 more years

P Møller - Mutagenesis, 2018 - academic.oup.com
During the last 30 years, the comet assay has become widely used for the measurement of
DNA damage and repair in cells and tissues. A landmark achievement was reached in 2016 …

The comet assay in higher terrestrial plant model: review and evolutionary trends

C Lanier, N Manier, D Cuny, A Deram - Environmental Pollution, 2015 - Elsevier
The comet assay is a sensitive technique for the measurement of DNA damage in individual
cells. Although it has been primarily applied to animal cells, its adaptation to higher plant …

Recommendations for increasing alkaline comet assay reliability in plants

B Pourrut, E Pinelli, V Celiz Mendiola, J Silvestre… - …, 2015 - academic.oup.com
In plants, an increasing interest for the comet assay was shown in the last decade. This
versatile technique appears to be promising to detect the genotoxic effect of pollutants and …

Recent applications of the comet assay: A report from the international comet assay workshop 2019

G Gajski, S Langie, A Zhanataev - Toxicology letters, 2020 - Elsevier
Abstract The International Comet Assay Workshops (ICAW) are a series of scientific
conferences dealing with different aspects of the comet assay. The assay itself is a simple …