Tumor microenvironment (TME) is a specialized ecosystem of host components, designed
by tumor cells for successful development and metastasis of tumor. With the advent of 3D …

The tumor microenvironment (TME) is being increasingly recognized as a key factor in
multiple stages of disease progression, particularly local resistance, immune-escaping, and …

Genetic alterations drive tumor onset and progression. However, the cross‑talk between
tumor cells and the benign components of the surrounding stroma can also promote the …

The complexity of the cellular and acellular players within the tumor microenvironment
(TME) allows for significant variation in TME constitution and role in anticancer treatment …

The tumor microenvironment (TME) consists of cells, soluble factors, signaling molecules,
extracellular matrix, and mechanical cues that can promote neoplastic transformation …

Recent advances in cancer immunology have led to a better understanding of the role of the
tumor microenvironment (TME) in tumor initiation, progression, and metastasis. Tumors can …

Tumor microenvironment (TME) is a host for a complex network of heterogeneous stromal
cells with overlapping or opposing functions depending on the dominant signals within this …

The tumor microenvironment (TME) influences tumor growth, metastatic spread and
response to treatment. Often immunosuppression, mediated by the TME, impairs a beneficial …

The understanding of the tumor microenvironment (TME) has been expanding in recent
years in the context of interactions among different cell types, through direct cell–cell …

Cancer development is highly associated to the physiological state of the tumor
microenvironment (TME). Despite the existing heterogeneity of tumors from the same or from …