Biological roles of adenine methylation in RNA

K Boulias, EL Greer - Nature Reviews Genetics, 2023 - nature.com
Abstract N 6-Methyladenosine (m6A) is one of the most abundant modifications of the
epitranscriptome and is found in cellular RNAs across all kingdoms of life. Advances in …

N6-methyladenosine-mediated gene regulation and therapeutic implications

Y Liu, D Yang, T Liu, J Chen, J Yu, P Yi - Trends in molecular medicine, 2023 - cell.com
Abstract N6-methyladenosine (m 6 A) RNA methylation is the most abundant form of mRNA
modification in eukaryotes and is at the front line of biological and biomedical research. This …

RNA m6A methylation across the transcriptome

E Sendinc, Y Shi - Molecular cell, 2023 - cell.com
Since the early days of foundational studies of nucleic acids, many chemical moieties have
been discovered to decorate RNA and DNA in diverse organisms. In mammalian cells, one …

The dynamic epitranscriptome: N6-methyladenosine and gene expression control

KD Meyer, SR Jaffrey - Nature reviews Molecular cell biology, 2014 - nature.com
Abstract N 6-methyladenosine (m6A) is a modified base that has long been known to be
present in non-coding RNAs, ribosomal RNA, polyadenylated RNA and at least one …

RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation

Y Yue, J Liu, C He - Genes & development, 2015 - genesdev.cshlp.org
N 6-methyladenosine (m6A) is the most prevalent and internal modification that occurs in the
messenger RNAs (mRNA) of most eukaryotes, although its functional relevance remained a …

Reading, writing and erasing mRNA methylation

S Zaccara, RJ Ries, SR Jaffrey - Nature reviews Molecular cell biology, 2019 - nature.com
RNA methylation to form N 6-methyladenosine (m6A) in mRNA accounts for the most
abundant mRNA internal modification and has emerged as a widespread regulatory …

N6-methyladenosine–encoded epitranscriptomics

N Liu, T Pan - Nature structural & molecular biology, 2016 - nature.com
Abstract N 6-methyladenosine (m 6 A) is the most abundant internal modification in
eukaryotic mRNA. Recent discoveries of the locations, functions and mechanisms of m 6 A …

The emerging roles of N6-methyladenosine RNA methylation in human cancers

H Shen, Y Lan, Y Zhao, Y Shi, J Jin, W Xie - Biomarker Research, 2020 - Springer
Abstract N6-methyladenosine (m 6 A) is the most abundant form of mRNA modification in
eukaryotes. It affects various aspects of RNA metabolism, including nuclear export …

[HTML][HTML] scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells

M Tegowski, MN Flamand, KD Meyer - Molecular cell, 2022 - cell.com
Summary N 6-methyladenosine (m 6 A) is an abundant RNA modification that plays critical
roles in RNA regulation and cellular function. Global m 6 A profiling has revealed important …

N6-Methyl-Adenosine (m6A) in RNA: An Old Modification with A Novel Epigenetic Function

Y Niu, X Zhao, YS Wu, MM Li, XJ Wang… - Genomics, proteomics …, 2013 - academic.oup.com
Abstract N6-methyl-adenosine (m6A) is one of the most common and abundant
modifications on RNA molecules present in eukaryotes. However, the biological significance …