Elastin is expressed in most tissues that require elastic recoil. The protein first appeared
coincident with the closed circulatory system, and was critical for the evolutionary success of …

The mechanical properties of the lung are largely determined by the connective tissue
networks laid down during development. The macromolecules most important for lung …

Elastic fibers are important for elasticity and extensibility of lung tissue. In the developing
lung, elastic fibers appear in greatest numbers during the process or period of …

Elastin is a major component of the mammalian lung, predominantly found in the alveoli.
Destruction of alveolar elastic fibers is implicated in the pathogenic mechanism of …

Elastin is a critical component of the lung interstitium, providing the property of recoil to the
vascular, conducting airway, and terminal airspace compartments of the lung. Elastic fibers …

The important role that elastin plays in the development and proper function of lung has long
been recognized. Also, the intimate connection between pulmonary emphysema and the …

It is essential that the framework of all multicellular organisms should include some materials
with high tensile strength and rigidity, such as bone and collagen, to maintain shape and …

Cigarette smoking is the strongest risk factor for emphysema. However, sensitivity to
cigarette smoke-induced emphysema is highly variable, and numerous genetic and …

抄録 Collagen and elastin fibers are the major components of the lung connective tissue, but
their spatial organization has not been well documented. We have demonstrated the three …

Elastin, an important structural protein of the extracellular matrix, confers elastic properties
on the pulmonary alveolar interstitium. In the alveolar wall, elastin is primarily produced …