Extracellular vesicles (EVs) including exosomes, microvesicles (MVs), and apoptotic bodies,
are small membrane vesicular structures that are released during cell activation …

Adipose tissue is comprised of a heterogeneous population of cells that co-operate to
perform diverse physiological roles including endocrine-related functions. The endocrine …

Extracellular vesicles (EVs) are submicron-sized lipid envelopes that are produced and
released from a parent cell and can be taken up by a recipient cell. EVs are capable of …

Abstract Extracellular vesicles (EVs), membrane-contained vesicles released by most cell
types, have attracted a large amount of research interest over the past decade. Because of …

Functional adipose tissue is essential for homeostatic maintenance of systemic metabolism.
As such, adipose tissue dysfunction, like that seen in the obese state, directly contributes to …

Metabolic homeostasis emerges from the complex, multidirectional crosstalk between key
metabolic tissues including adipose tissue, liver, and skeletal muscle. This crosstalk …

Adipose tissue (AT) is a highly heterogeneous and dynamic organ that plays important roles
in regulating energy metabolism and insulin sensitivity. In addition to its classical roles in …

Adipose tissue plays a key role in the development of insulin resistance and its pathological
sequelae, such as type 2 diabetes and non-alcoholic fatty liver disease. Dysfunction in the …

Childhood obesity continues to be a major public health concern. Obesity causes various
metabolic complications, including insulin resistance, type 2 diabetes mellitus (T2DM), non …

Recently, the emerging roles of adipocyte-derived extracellular vesicles (EVs) linking
obesity and its comorbidities have been recognized. In obese subjects, adipocytes are …