Embryonic losses constitute a major burden for reproductive efficiency of farm animals.
Pregnancy losses in ungulate species, which include cattle, pigs, sheep and goats, majorly …

Preimplantation development is well conserved across mammalian species, but major
differences in developmental kinetics, regulation of early lineage differentiation and …

The majority of embryonic loss in cattle occurs before maternal recognition of pregnancy, at
around Day 16 postconception. The origin of the embryo can have a significant impact on …

Conceptus-maternal communication is vital for the successful establishment and
maintenance of pregnancy, yet relatively little information exists for many of the mechanisms …

Embryonic mortality in both farm animals and humans occurs most frequently during the first
few weeks after conception. It can be attributed to abnormalities in the earliest …

A detailed morphological staging system for cattle embryos at stages following blastocyst
hatching and preceding gastrulation is presented here together with spatiotemporal …

Many studies have shown that in vitro culture can negatively impact preimplantation
development. This necessitates some selection criteria for identifying the best-suited …

The molecular basis of ungulate and non-rodent conceptus elongation and gastrulation
remains poorly understood; however, use of state-of-the-art genomic technologies is …

Embryonic and extra-embryonic lineages are separated at the blastocyst stage in the mouse
at the onset of implantation but well ahead of implantation in most mammals. To provide …

Preimplantation embryos undergo zygotic genome activation and lineage specification
resulting in three distinct cell types in the late blastocyst. The molecular mechanisms …