Background c-Kit is a receptor tyrosine kinase present in multiple cell types, including
vascular smooth muscle cells (SMC). However, little is known about how c-Kit influences …

The stem cell factor (SCF) binds to c-Kit in endothelial cells, thus activating downstream
signaling and angiogenesis. Herein, we examined the role of G protein subunit alpha …

Rationale: Transplantation-accelerated arteriosclerosis is one of the major challenges for
long-term survival of patients with solid organ transplantation. Although stem/progenitor cells …

The receptor tyrosine kinase c-Kit plays an integral role in maintaining β-cell mass and
function. Although c-Kit receptor signaling promotes angiogenesis in multiple cell types, its …

We investigated the role of c-Kit and the membrane-bound ligand (mbKitL) in endothelial
progenitor cell (EPC) recruitment by microvascular endothelial cells (ECs). We …

Canine cutaneous mast cell tumour (CMCT) is ac‐Kit driven tumour sharing similar c‐Kit
aberrations found in human gastrointestinal stromal tumour. CMCT is classified into three …

Renal cell carcinoma (RCC) is the most frequent renal tumor and its incidence is increasing
worldwide. Tumor angiogenesis is known to play a crucial role in the etiopathogenesis of …

Objective—Stem cell factor (SCF) through its cognate receptor, the tyrosine kinase c-kit,
promotes survival and biological functions of hematopoietic stem cells and progenitors …

In recent studies we have shown that the expression of stem cell factor (SCF) in human
endothelial cells is regulated by inflammatory processes. Gram-negative bacteria …

Mobilization into peripheral blood of bone marrow-derived cells including hematopoietic
stem cells (HSCs) and endothelial progenitor cells (EPCs), is regulated by …