Long noncoding RNAs (lncRNAs) have abundant content and extensive functions that
regulate the expression of genes at multiple levels. Recently, transcriptome-wide analysis …

The broad application of next-generation sequencing technologies in conjunction with
improved bioinformatics has helped to illuminate the complexity of the transcriptome, both in …

The prevalence of metabolic diseases, including type 2 diabetes and metabolic dysfunction-
associated steatotic liver disease (MASLD), is steadily increasing. Although many risk …

Long non-coding RNAs (lncRNAs) have become important regulators of gene expression
because they affect a wide range of biological processes, such as cell growth, death …

Single cell organisms can surprisingly exceed the number of human protein-coding genes,
which are thus not at the origin of the complexity of an organism. In contrast, the relative …

Only a small fraction of the human genome corresponds to protein-coding genes.
Historically, the vast majority of genomic sequence was dismissed as transcriptionally silent …

Long noncoding RNAs (lncRNAs) are sensitive to changing environments and play key
roles in health and disease. Emerging evidence indicates that lncRNAs regulate gene …

Type 2 diabetes is a complex metabolic disorder characterized by insulin resistance and
pancreatic β-cell dysfunction. Deregulated glucose and lipid metabolism are the primary …

Long noncoding RNAs (lncRNAs) have been implicated in many biological processes.
However, due to the unique nature of lncRNAs and the consequential difficulties associated …

Long non-coding RNAs (lncRNAs) are a type of non-coding RNA with a length that exceeds
200 nucleotides. Previous studies have shown that lncRNAs play an important role in the …