Novel ketamine and zinc treatment for anorexia nervosa and the potential beneficial interactions with the gut microbiome

R Elwyn, J Mitchell, MR Kohn, C Driver, P Hay… - Neuroscience & …, 2023 - Elsevier
Anorexia nervosa (AN) is a severe illness with diverse aetiological and maintaining
contributors including neurobiological, metabolic, psychological, and social determining …

Ketamine and zinc: treatment of anorexia nervosa via dual NMDA receptor modulation

JS Mitchell, DF Hermens, MR Bennett, AT Can… - CNS drugs, 2023 - Springer
Anorexia nervosa is a disorder associated with serious adverse health outcomes, for which
there is currently considerable treatment ineffectiveness. Characterised by restrictive eating …

Anorexia nervosa, zinc deficiency and the glutamate system: The ketamine option

DF Hermens, G Simcock, M Dutton, AP Bouças… - Progress in Neuro …, 2020 - Elsevier
Anorexia nervosa (AN) is a severe, biological brain disorder with significant medical risks
and a tenacious development over time. Unfortunately, few treatments show efficacy in …

O6. Oral Ketamine and Zinc Supplementation Trial for Anorexia Nervosa

R Elwyn, J Mitchell, A Can, M Dutton… - Journal of Eating …, 2024 - research.usc.edu.au
This study is an open-label, dose-ranging clinical trial aiming to explore the safety, feasibility
and tolerability of a sub-anaesthetic dose of oral ketamine and combined zinc …

The impact of starvation on the microbiome and gut-brain interaction in anorexia nervosa

J Seitz, M Belheouane, N Schulz, A Dempfle… - Frontiers in …, 2019 - frontiersin.org
Interactions between the gut microbiome and the brain are of increasing interest to both
researchers and clinicians. Evidence is mounting on the causal role of an altered gut …

[HTML][HTML] Gut-Brain Interactions: Implications for a Role of the Gut Microbiota in the Treatment and Prognosis of Anorexia Nervosa

D Igudesman, M Sweeney, I Carroll… - … Clinics of North …, 2019 - ncbi.nlm.nih.gov
Through their effects on the intestinal epithelium and immunity, gut microbes and their
fermentative byproducts can influence metabolic and psychological health parameters in …

[PDF][PDF] Zinc supplementation in anorexia nervosa

JM Greenblatt, D Delane - Journal of Orthomolecular Medicine, 2018 - isom.ca
Every 62 minutes, someone in the United States dies as a direct result of an eating disorder
(Eating Disorders Coalition, 2016). That fatality is most likely linked to Anorexia Nervosa …

Are the Effects of Malnutrition on the Gut Microbiota–Brain Axis the Core Pathologies of Anorexia Nervosa?

S Frostad - Microorganisms, 2022 - mdpi.com
Anorexia nervosa (AN) is a disabling, costly, and potentially deadly illness. Treatment failure
and relapse after treatment are common. Several studies have indicated the involvement of …

[PDF][PDF] Are the effects of malnutrition on the gut microbiota-brain axis the core pathologies of anorexia nervosa? Microorganisms 2022; 10: 1486

S Frostad - 2022 - academia.edu
Anorexia nervosa (AN) is a disabling, costly, and potentially deadly illness. Treatment failure
and relapse after treatment are common. Several studies have indicated the involvement of …

Gut microbiome-brain interactions in anorexia nervosa: Potential mechanisms and regulatory strategies

R Zhu, P Tian, H Zhang, G Wang, W Chen - Neuropharmacology, 2023 - Elsevier
Anorexia nervosa (AN) is a psychiatric disorder characterised by malnutrition, fear of weight
gain, and body image disturbances. The aetiology of AN is complex, and may involve …