Multiple sclerosis (MS) is a neuro-inflammatory and neurodegenerative disease that is most
prevalent in Northern Europe. Although it is known that inherited risk for MS is located within …

INTRODUCTION Multiple sclerosis (MS) is an inflammatory and degenerative disease of the
central nervous system (CNS) that often presents in young adults. Over the past decade …

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system
underpinned by partially understood genetic risk factors and environmental triggers and …

Abstract The Holocene (beginning around 12,000 years ago) encompassed some of the
most significant changes in human evolution, with far-reaching consequences for the …

Multiple sclerosis is a common disease of the central nervous system in which the interplay
between inflammatory and neurodegenerative processes typically results in intermittent …

Monozygotic or 'identical'twins have been widely studied to dissect the relative contributions
of genetics and environment in human diseases. In multiple sclerosis (MS), an autoimmune …

We assembled and analyzed genetic data of 47,351 multiple sclerosis (MS) subjects and
68,284 control subjects and establish a reference map of the genetic architecture of MS that …

Genetic predisposition to multiple sclerosis (MS) only explains a fraction of the disease risk;
lifestyle and environmental factors are key contributors to the risk of MS. Importantly, these …

Multiple sclerosis (MS) is a neuroinflammatory disease with a relapsing–remitting disease
course at early stages, distinct lesion characteristics in cortical grey versus subcortical white …

Multiple sclerosis (MS) is a chronic inflammatory disorder characterized by multifocal
damage of myelin in the central neryous system (CMS). The prevalence of this putative …