Methods: In this research, we determined the promoter methylation status of four tumor
suppressor genes (SLC5A8, RASSF1, MGMT, and DNMT1) and compared the results of 55 …

The aim of this study was to evaluate the frequency (as qualitative analysis) and level (as
quantitative analysis) of promoter hypermethylation of four genes, P16, TSHR, RASSF1A …

Circulating cell‐free DNA (cfDNA) has been considered as a diagnostic source to track
genetic and epigenetic alterations in cancer. We aimed to study mutation in addition to the …

Background Epigenetic alterations such as DNA methylation are widespread cancer,
contributing to tumorigenesis and acting as markers for prognostication. Papillary thyroid …

Background Breast cancer is the most common malignancy in women caused by genetic
and epigenetic changes. Promoter DNA methylation in tumor suppressor gene plays a major …

Context: Cancer-specific molecular markers are needed to supplement the cytopathological
assessment of thyroid tumors, because a majority of patients with cytologically indeterminate …

Genome-wide hypomethylation and hypermethylation at CpG promoters are common in
cancer. To date, little is known about global methylation changes in follicular thyroid cancer …

Background Esophageal squamous cell carcinoma is one of the most common
malignancies in the world. Studies have confirmed that there are many genes abnormally …

Objective: The tumor suppressor gene methylation lead to gene silencing, it plays an
important role in thyroid tumor occurrence and development. This study examined the tumor …

Purpose: The methylation profile of nasopharyngeal carcinoma (NPC) has been
investigated by a candidate gene approach. Experimental Design: Four NPC cell lines, 4 …