Structure and size determination of bacteriophage P2 and P4 procapsids: function of size responsiveness mutations

AD Dearborn, P Laurinmaki, P Chandramouli… - Journal of structural …, 2012 - Elsevier
Bacteriophage P4 is dependent on structural proteins supplied by a helper phage, P2, to
assemble infectious virions. Bacteriophage P2 normally forms an icosahedral capsid with T …

[HTML][HTML] Assembly of bacteriophage P2 and P4 procapsids with internal scaffolding protein

S Wang, JR Chang, T Dokland - Virology, 2006 - Elsevier
Assembly of the E. coli bacteriophage P2 into an icosahedral capsid with T= 7 symmetry is
dependent on the gpN capsid protein, the gpQ connector protein and the gpO internal …

Bacteriophage P2 and P4 assembly: alternative scaffolding proteins regulate capsid size

OJ Marvik, P Sharma, T Dokland, BH Lindqvist - Virology, 1994 - Elsevier
The capsid protein of bacteriophage P2, encoded by the N gene, can assemble into
icosahedraf capsids of two possible sizes, with diameters of 60 and 45 nm, respectively …

Bacteriophage P2 and P4 morphogenesis: assembly precedes proteolytic processing of the capsid proteins

OJ Marvik, E Jacobsen, T Dokland, BH Lindqvist - Virology, 1994 - Elsevier
Several of the structural proteins of phage P2 and its satellite P4 undergo proteolytic
processing during development of mature phage particles. Here, we report that uncleaved …

In vitro assembly of bacteriophage P4 procapsids from purified capsid and scaffolding proteins

S Wang, P Palasingam, RH Nøkling, BH Lindqvist… - Virology, 2000 - Elsevier
Bacteriophage P4 is a satellite virus of bacteriophage P2, which has acquired the ability to
utilize the structural gene products of P2 to assemble its own capsid. The normal P2 capsid …

A molecular staple: D-loops in the I domain of bacteriophage P22 coat protein make important intercapsomer contacts required for procapsid assembly

NG D'Lima, CM Teschke - Journal of virology, 2015 - Am Soc Microbiol
Bacteriophage P22, a double-stranded DNA (dsDNA) virus, has a nonconserved 124-amino-
acid accessory domain inserted into its coat protein, which has the canonical HK97 protein …

[HTML][HTML] Functional domains of the bacteriophage P2 scaffolding protein: identification of residues involved in assembly and protease activity

JR Chang, MS Spilman, CM Rodenburg, T Dokland - Virology, 2009 - Elsevier
Bacteriophage P2 encodes a scaffolding protein, gpO, which is required for correct
assembly of P2 procapsids from the gpN major capsid protein. The 284 residue gpO protein …

The structure of P4 procapsids produced by coexpression of capsid and external scaffolding proteins

T Dokland, S Wang, BH Lindqvist - Virology, 2002 - Elsevier
The double-stranded DNA bacteriophage P4 has a T= 4 icosahedral arrangement of the
gpN capsid protein derived from the P2 helper phage. The precursor procapsids in addition …

Assembly and capsid expansion mechanism of bacteriophage P22 revealed by high-resolution cryo-EM structures

H Xiao, J Zhou, F Yang, Z Liu, J Song, W Chen, H Liu… - Viruses, 2023 - mdpi.com
The formation of many double-stranded DNA viruses, such as herpesviruses and
bacteriophages, begins with the scaffolding-protein-mediated assembly of the procapsid …

Bacteriophage P2 and P4 morphogenesis: protein processing and capsid size determination

S Rishovd, BH Lindqvist - Virology, 1992 - Elsevier
An interesting feature of the bacteriophage P2–P4 system is the switch in size between a
large P2 (60 nm) and a small P4 (45 nm) capsid. We have investigated whether the protein …