We examined the relationships of antemortem vascular risk factors to postmortem
cerebrovascular and Alzheimer's disease (AD) pathologies. Eighty-four AD patients …

Vascular lesions in the brain are common with advancing age; however, the independent
and cumulative contributions of postmortem vascular lesions to antemortem cognitive status …

Objective: To test the hypothesis that patients with Alzheimer disease (AD) who have
vascular risk factors have a worse prognosis over 18 months vs those without such risk …

Importance Identifying asymptomatic individuals at high risk of impending cognitive decline
because of Alzheimer disease is crucial for successful prevention of dementia. Vascular risk …

Numerous studies have linked individual vascular factors to dementia including Alzheimer's
disease (AD). We investigated different vascular risk profiles in relation to dementia and AD …

The vascular hypothesis of Alzheimer's disease (AD) which we first proposed in 1993, has
become a useful concept in identifying vascular risk factors for AD or vascular dementia that …

BACKGROUND: A substantial body of evidence collected from epidemiologic, correlative,
and experimental studies strongly associates atherosclerotic vascular disease (AVD) with …

A series of strokes leading to dementia was once referred to as multi-infarct dementia,
characterized by a stepwise decline in cognitive function. 12 Nowadays, multi-infarct …

Vascular factors are now established risk factors for cognitive decline, both for dementia and
its two main subtypes: Alzheimer's disease (AD) and vascular dementia. Their impact likely …

Background—The main stumbling block in the clinical management and in the search for a
cure of Alzheimer disease (AD) is that the cause of this disorder has remained uncertain …