Zi Shen Wan Fang Attenuates Neuroinflammation and Cognitive Function Via Remodeling the Gut Microbiota in Diabetes-Induced Cognitive Impairment Mice

J Shi, Q Yin, L Zhang, Y Wu, P Yi, M Guo, H Li… - Frontiers in …, 2022 - frontiersin.org
Background: Cognitive dysfunction is a critical complication of diabetes mellitus, and there
are still no clinically approved drugs. Zi Shen Wan Fang (ZSWF) is an optimized prescription …

[HTML][HTML] ZiBuPiYin recipe improves cognitive decline by regulating gut microbiota in Zucker diabetic fatty rats

C Gu, W Zhou, W Wang, H Xiang, H Xu, L Liang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Numerous researches supported that microbiota can influence behavior and modulate
cognitive function through “microbiota-gut-brain” axis. Our previous study has demonstrated …

Compound Danshen Dripping Pills moderate intestinal flora and the TLR4/MyD88/NF-κB signaling pathway in alleviating cognitive dysfunction in type 2 diabetic KK …

X Fan, Y Zhang, Y Song, Y Zhao, Y Xu, F Guo, M Shao… - Phytomedicine, 2023 - Elsevier
Backgroud Bidirectional communications between the gut microbiota and the brain may play
a critical role in diabetes-related cognitive impairment. Compound Danshen Dripping Pills …

ZiBuPiYin Recipe Prevented and Treated Cognitive Decline in ZDF Rats With Diabetes-Associated Cognitive Decline via Microbiota–Gut–Brain Axis Dialogue

T Bi, R Feng, L Zhan, W Ren, X Lu - Frontiers in Cell and …, 2021 - frontiersin.org
Gut microbiota is becoming one of the key determinants in human health and disease. Shifts
in gut microbiota composition affect cognitive function and provide new insights for the …

Effect of tanshinone IIA on gut microbiome in diabetes-induced cognitive impairment

Y Zheng, X Zhou, C Wang, J Zhang, D Chang… - Frontiers in …, 2022 - frontiersin.org
Diabetes-induced cognitive impairment (DCI) presents a major public health risk among the
aging population. Previous clinical attempts on known therapeutic targets for DCI, such as …

Microbiota from healthy mice alleviates cognitive decline via reshaping the gut-brain metabolic axis in diabetic mice

Q Zhao, J Chen, M Wu, X Yin, Q Jiang, H Gao… - Chemico-Biological …, 2023 - Elsevier
Diabetic cognitive decline has been associated with the gut microbial disorders, but its
potential gut-brain axis mechanisms remain unclear. Herein we transplanted the gut …

Lingguizhugan decoction ameliorates cognitive impairment in AD-like mice by influencing the microbiome–gut–brain axis mediated by SCFAs

L Du, J Chen, J Yan, H Xie, L Wang, R Wang, X Han… - Phytomedicine, 2024 - Elsevier
Background Lingguizhugan (LGZG) decoction, an ancient Chinese herbal remedy
originating from the Eastern Han Dynasty, consists of Poria cocos, Cinnamomi ramulus …

Jiang Tang San Hao Formula exerts its anti-diabetic effect by affecting the gut-microbiota-brain axis

Y Bai, Y Zhao, J Jin, Z Ye, H Fan, D Zhao, S Gao - Phytomedicine, 2024 - Elsevier
Background Type 2 diabetes is a complex metabolic disorder characterized by insulin
resistance and impaired insulin secretion, with growing evidence highlighting the critical role …

Live and pasteurized Akkermansia muciniphila ameliorates diabetic cognitive impairment by modulating gut microbiota and metabolites in db/db mice

Y Du, Y An, Y Song, N Li, J Zheng, Y Lu - Experimental Neurology, 2024 - Elsevier
The established role of disturbances in the microbiota-gut-brain axis in the development of
diabetic cognitive impairment (DCI) has long been recognized. It has shown the potential of …

Transplant of fecal microbiota from healthy young mice relieves cognitive defects in late-stage diabetic mice by reducing metabolic disorders and neuroinflammation

X Ye, Q Jiang, M Wu, Q Ye, H Zheng - Acta Pharmacologica Sinica, 2024 - nature.com
Fecal microbiota transplant (FMT) is becoming as a promising area of interest for treating
refractory diseases. In this study, we investigated the effects of FMT on diabetes-associated …