[HTML][HTML] Sex: a significant risk factor for neurodevelopmental and neurodegenerative disorders

P Pinares-Garcia, M Stratikopoulos, A Zagato, H Loke… - Brain sciences, 2018 - mdpi.com
Males and females sometimes significantly differ in their propensity to develop neurological
disorders. Females suffer more from mood disorders such as depression and anxiety …

Sex, hormones, and genotype interact to influence psychiatric disease, treatment, and behavioral research

AR Gobinath, E Choleris… - Journal of neuroscience …, 2017 - Wiley Online Library
Sex differences exist in the vulnerability, incidence, manifestation, and treatment of
numerous neurological and psychiatric diseases. Despite this observation prominent in the …

Biological factors underlying sex differences in neurological disorders

H Loke, V Harley, J Lee - The international journal of biochemistry & cell …, 2015 - Elsevier
The prevalence, age of onset, pathophysiology, and symptomatology of many neurological
and neuropsychiatric conditions differ significantly between males and females. Females …

[HTML][HTML] Sex representation in neurodegenerative and psychiatric disorders' preclinical and clinical studies

M DuMont, A Agostinis, K Singh, E Swan, Y Buttle… - Neurobiology of …, 2023 - Elsevier
Many studies show the importance of biological sex for the onset, progression, and
response to treatment in brain disorders. In line with these reports, health agencies have …

Genetic and epigenetic factors underlying sex differences in the regulation of gene expression in the brain

VS Ratnu, MR Emami, TW Bredy - Journal of neuroscience …, 2017 - Wiley Online Library
There are inherent biological differences between males and females that contribute to sex
differences in brain function and to many sex‐specific illnesses and disorders. Traditionally …

Sex and gender differences in central nervous system‐related disorders

E Zagni, L Simoni, D Colombo - Neuroscience journal, 2016 - Wiley Online Library
There are important sex differences in the brain that seem to arise from biology as well as
psychosocial influences. Sex differences in several aspects of human behavior and …

[HTML][HTML] Sex and gender differences in neurodegenerative diseases: challenges for therapeutic opportunities

A Bianco, Y Antonacci, M Liguori - International journal of molecular …, 2023 - mdpi.com
The term “neurodegenerative diseases”(NDs) identifies a group of heterogeneous diseases
characterized by progressive loss of selectively vulnerable populations of neurons, which …

Why sex hormones matter for neuroscience: A very short review on sex, sex hormones, and functional brain asymmetries

M Hausmann - Journal of Neuroscience Research, 2017 - Wiley Online Library
Biological sex and sex hormones are known to affect functional cerebral asymmetries
(FCAs). Men are generally more lateralized than women. The effect size of this sex …

[HTML][HTML] Chromosomal and environmental contributions to sex differences in the vulnerability to neurological and neuropsychiatric disorders: Implications for …

PN Pallier, M Ferrara, F Romagnolo, MT Ferretti… - Progress in …, 2022 - Elsevier
Neurological and neuropsychiatric disorders affect men and women differently. Multiple
sclerosis, Alzheimer's disease, anxiety disorders, depression, meningiomas and late-onset …

Why sex matters for neuroscience

L Cahill - Nature reviews neuroscience, 2006 - nature.com
A rapidly burgeoning literature documents copious sex influences on brain anatomy,
chemistry and function. This article highlights some of the more intriguing recent discoveries …