Liposomal drug delivery to manage nontuberculous mycobacterial pulmonary disease and other chronic lung infections

JD Chalmers, J van Ingen… - European …, 2021 - Eur Respiratory Soc
Nontuberculous mycobacterial (NTM) pulmonary disease is a chronic respiratory infection
associated with declining lung function, radiological deterioration and significantly increased …

Inhaled liposomal antimicrobial delivery in lung infections

M Bassetti, A Vena, A Russo, M Peghin - Drugs, 2020 - Springer
The management of difficult-to-treat acute and chronic respiratory infections (infections in
cystic fibrosis, non-cystic fibrosis bronchiectasis, immunocompromised and mechanically …

Dual antitubercular drug loaded liposomes for macrophage targeting: development, characterisation, ex vivo and in vivo assessment

P Shrivastava, L Gautam, R Sharma… - Journal of …, 2021 - Taylor & Francis
Aim The present study was conducted to formulate and investigate liposomes for the dual
drug delivery based on anti-tubercular drug (s) combination ie Isoniazid (INH) and …

Pulmonary delivery of liposomes

H Schreier, RJ Gonzalez-Rothi, AA Stecenko - Journal of Controlled …, 1993 - Elsevier
An overview of current data on pulmonary delivery of liposomes is provided, entailing fate of
aerosols in the respiratory tract, physicochemical characterization of liposome aerosols, their …

Liposome-based drug delivery to alveolar macrophages

SP Vyas, K Khatri - Expert opinion on drug delivery, 2007 - Taylor & Francis
The recent development of liposomal formulations compatible with aerosol delivery has
expanded the potential to utilise chemotherapeutic agents directly targeted to the lungs …

New delivery systems–Liposomes for pulmonary delivery of antibacterial drugs

AMA Elhissi, SR Dennison, W Ahmed… - Novel antimicrobial …, 2014 - Wiley Online Library
Liposomes are established drug carriers for inhalation owing to their biocompatibility,
biodegradability, and ability to entrap drugs and prolong their therapeutic effects in the …

Inhalable liposomes for treating lung diseases: Clinical development and challenges

P Ponkshe, S Feng, C Tan - Biomedical Materials, 2021 - iopscience.iop.org
Inhalation delivery of liposomal drugs has distinct advantages for the treatment of pulmonary
diseases. Inhalable liposomes of several drugs are currently undergoing clinical trials for a …

Liposomes for pulmonary drug delivery

J Swaminathan, C Ehrhardt - Controlled pulmonary drug delivery, 2011 - Springer
Liposomes have been widely used in pulmonary drug delivery for multiple applications
including solubilization, sustained release, cellular and intracellular targeting, minimization …

Liposomes for pulmonary drug delivery: the role of formulation and inhalation device design

A Elhissi - Current pharmaceutical design, 2017 - ingentaconnect.com
Liposomes are established drug carriers for inhalation owing to their safety and ability to
provide controlled drug release in the lung. These carriers can entrap a wide range of …

Amikacin liposome inhalation suspension (ALIS) penetrates non-tuberculous mycobacterial biofilms and enhances amikacin uptake into macrophages

J Zhang, F Leifer, S Rose, DY Chun, J Thaisz… - Frontiers in …, 2018 - frontiersin.org
Non-tuberculous mycobacteria (NTM) cause pulmonary infections in patients with structural
lung damage, impaired immunity, or other risk factors. Delivering antibiotics to the sites of …