[PDF][PDF] Synergistic effect of ponatinib and epigallocatechin-3-gallate induces apoptosis in chronic myeloid leukemia cells through altering expressions of cell cycle …
Purpose: Ponatinib (P) has been used for the treatment of chronic myeloid leukemia (CML)
and it is known that inhibition of BCR-ABL fusion protein by ponatinib induces apoptosis of …
and it is known that inhibition of BCR-ABL fusion protein by ponatinib induces apoptosis of …
(−)‐Epigallocatechin‐3‐gallate induces cell apoptosis in chronic myeloid leukaemia by regulating Bcr/Abl‐mediated p38‐MAPK/JNK and JAK 2/STAT 3/AKT …
X Xiao, K Jiang, Y Xu, H Peng, Z Wang… - Clinical and …, 2019 - Wiley Online Library
Summary Epigallocatechin‐3‐gallate (EGCG), a major polyphenolic constituent of green
tea, possesses remarkable chemopreventive and therapeutic potential against various types …
tea, possesses remarkable chemopreventive and therapeutic potential against various types …
[HTML][HTML] Effect of Epigallocatechin-3-gallate (EGCG) on cell proliferation inhibition and apoptosis induction in lymphoblastic leukemia cell line
M Ghasemi-Pirbaluti, B Pourgheysari… - Journal of …, 2015 - herbmedpharmacol.com
Introduction: Acute lymphoblastic leukemia (ALL) is one of the malignant proliferations of
lymphoid cells in the early stages of differentiation and accounts for ¾ of all cases of …
lymphoid cells in the early stages of differentiation and accounts for ¾ of all cases of …
[HTML][HTML] Epigallocatechin‑3‑gallate induces apoptosis in acute promyelocytic leukemia cells via a SHP‑1‑p38α MAPK‑Bax cascade
L Gan, L Zhong, Z Shan, C Xiao, T Xu… - Oncology …, 2017 - spandidos-publications.com
Acute promyelocytic leukemia (APL) is characterized by a specific chromosomal translation,
resulting in a fusion gene that affects the differentiation, proliferation and apoptosis of APL …
resulting in a fusion gene that affects the differentiation, proliferation and apoptosis of APL …
A derivative of epigallocatechin‐3‐gallate induces apoptosis via SHP‐1‐mediated suppression of BCR‐ABL and STAT3 signalling in chronic myelogenous leukaemia
Background and Purpose Epigallocatechin‐3‐gallate (EGCG) is a component of green tea
known to have chemo‐preventative effects on several cancers. However, EGCG has limited …
known to have chemo‐preventative effects on several cancers. However, EGCG has limited …
[HTML][HTML] The critical role of PTEN/PI3K/AKT signaling pathway in shikonin-induced apoptosis and proliferation inhibition of chronic myeloid leukemia
Y Chen, T Wang, J Du, Y Li, X Wang, Y Zhou… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm.
Tyrosine kinase inhibitors (TKIs) are commonly used to treat CML; however, drug resistance …
Tyrosine kinase inhibitors (TKIs) are commonly used to treat CML; however, drug resistance …
[HTML][HTML] D-Pinitol treatment induced the apoptosis in human leukemia MOLT-4 cells by improved apoptotic signaling pathway
X Yao, K Shi, Y Yang, X Gu, W Tan, Q Wang… - Saudi Journal of …, 2020 - Elsevier
Cancer is still remain as a global burden with the 18.1 million and 9.6 million new cases and
mortlities, respectively estimated globally. Leukemia may arise at all ages varied from the …
mortlities, respectively estimated globally. Leukemia may arise at all ages varied from the …
GDC-0152 induces apoptosis through down-regulation of IAPs in human leukemia cells and inhibition of PI3K/Akt signaling pathway
R Hu, J Li, Z Liu, M Miao, K Yao - Tumor Biology, 2015 - Springer
The inhibitor of apoptosis proteins (IAPs) is closely related to leukemia apoptosis. The
present study was undertaken to determine the molecular mechanisms by which GDC-0152 …
present study was undertaken to determine the molecular mechanisms by which GDC-0152 …
(–)-Epigallocatechin-3-gallate induces apoptosis and differentiation in leukaemia by targeting reactive oxygen species and PIN1
FI Della Via, RN Shiraishi, I Santos, KP Ferro… - Scientific reports, 2021 - nature.com
Epigallocatechin-3-gallate (EGCG), the major active polyphenol extracted from green tea,
has been shown to induce apoptosis and inhibit cell proliferation, cell invasion …
has been shown to induce apoptosis and inhibit cell proliferation, cell invasion …
Catechin, a green tea component, rapidly induces apoptosis of myeloid leukemic cells via modulation of reactive oxygen species production in vitro and inhibits tumor …
T Nakazato, K Ito, Y Miyakawa, K Kinjo… - …, 2005 - haematologica.org
BACKGROUND AND OBJECTIVES: The aim of this study was to investigate the possibility of
green tea polyphenol,(-)-epigallocatechin-3-gallate (EGCG) as a novel therapeutic agent for …
green tea polyphenol,(-)-epigallocatechin-3-gallate (EGCG) as a novel therapeutic agent for …