Genetic profile of advanced thyroid cancers in relation to distant metastasis
E Song, DE Song, J Ahn, TY Kim… - Endocrine-related …, 2020 - erc.bioscientifica.com
Major clinical challenges exist with differentiated thyroid cancers with distant metastases or
rare but aggressive types, such as poorly differentiated thyroid carcinomas and anaplastic …
rare but aggressive types, such as poorly differentiated thyroid carcinomas and anaplastic …
Genomic profiling of primary and metastatic thyroid cancers
The genetic repertoire of primary thyroid cancers (TCs) is well documented, but there is a
considerable lack of molecular profiling in metastatic TCs. Here, we retrieved and analyzed …
considerable lack of molecular profiling in metastatic TCs. Here, we retrieved and analyzed …
TERT, BRAF, and NRAS in Primary Thyroid Cancer and Metastatic Disease
M Melo, A Gaspar da Rocha, R Batista… - The Journal of …, 2017 - academic.oup.com
Context Little is known about the frequency of key mutations in thyroid cancer metastases
and its relationship with the primary tumor genotype. Objectives To evaluate the frequency of …
and its relationship with the primary tumor genotype. Objectives To evaluate the frequency of …
Highly concordant key genetic alterations in primary tumors and matched distant metastases in differentiated thyroid cancer
Background: Distant metastases uncommonly occur in differentiated thyroid carcinoma
(DTC), but they are a frequent cause of thyroid cancer–related death. Genomic alterations in …
(DTC), but they are a frequent cause of thyroid cancer–related death. Genomic alterations in …
Whole-exome sequencing of matched primary and metastatic papillary thyroid cancer
Background: Distant metastasis is a rare occurrence in thyroid cancer, and it can be
associated with poor prognosis. The genomic repertoires of various solid malignancies have …
associated with poor prognosis. The genomic repertoires of various solid malignancies have …
TERT promoter mutations identify a high-risk group in metastasis-free advanced thyroid carcinoma
C Bournaud, F Descotes, M Decaussin-Petrucci… - European Journal of …, 2019 - Elsevier
Background TERT promoter mutations are associated with adverse clinicopathological
characteristics in thyroid carcinomas and considered as a major indicator of poor outcomes …
characteristics in thyroid carcinomas and considered as a major indicator of poor outcomes …
Genomic landscape of metastatic papillary thyroid carcinoma and novel biomarkers for predicting distant metastasis
Papillary thyroid carcinoma (PTC) is the most common malignancy of the thyroid gland, with
a relatively high cure rate. Distant metastasis (DM) of PTC is uncommon, but when it occurs …
a relatively high cure rate. Distant metastasis (DM) of PTC is uncommon, but when it occurs …
Foundation one genomic interrogation of thyroid cancers in patients with metastatic disease requiring systemic therapy
NM Iñiguez-Ariza, S Jasim, MM Ryder… - The Journal of …, 2020 - academic.oup.com
Context Clinical applications of genomic assessment of thyroid cancers are rapidly evolving.
Objectives, Design, and Setting We studied tumor samples from patients with imminently …
Objectives, Design, and Setting We studied tumor samples from patients with imminently …
Molecular alterations in thyroid carcinoma
MRH Al Rasheed, B Xu - Surgical pathology clinics, 2019 - surgpath.theclinics.com
Thyroid carcinoma is the most common cancer in the endocrine system. Recent advances,
using next-generation sequencing, have shed light on the molecular pathogenesis of thyroid …
using next-generation sequencing, have shed light on the molecular pathogenesis of thyroid …
Genomic profiling of aggressive thyroid cancer in association with its clinicopathological characteristics
JH Kim, JY Jeong, AN Seo, NJY Park, M Kim, JY Park - in vivo, 2022 - iv.iiarjournals.org
Background/Aim: Poorly differentiated thyroid carcinoma (PDTC), anaplastic thyroid
carcinoma (ATC), and advanced DTC have poor outcomes. Materials and Methods: We …
carcinoma (ATC), and advanced DTC have poor outcomes. Materials and Methods: We …
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