[HTML][HTML] Leukotriene receptor antagonist, montelukast ameliorates L-Name-induced pre-eclampsia in rats through suppressing the IL-6/Jak2/STAT3 signaling pathway
WY Abdelzaher, G Mostafa-Hedeab, HA Bahaa… - Pharmaceuticals, 2022 - mdpi.com
Aims: To investigate the potential protective role of montelukast (Mont) in the pre-eclampsia
rat model induced by L-NG-Nitro arginine methyl ester (L-NAME). Methods and materials …
rat model induced by L-NG-Nitro arginine methyl ester (L-NAME). Methods and materials …
Montelukast, a leukotriene receptor antagonist abrogates lipopolysaccharide-induced toxicity and oxidative stress in rat liver
AM Mohamadin, AA Elberry, MA Elkablawy… - Pathophysiology, 2011 - Elsevier
Endotoxemia-induced hepatotoxicity is characterized by disturbed intracellular redox
balance, excessive reactive oxygen species (ROS) generation inducing DNA, proteins and …
balance, excessive reactive oxygen species (ROS) generation inducing DNA, proteins and …
Amelioration of sepsis-induced hepatic and ileal injury in rats by the leukotriene receptor blocker montelukast
Background: Sepsis is a generalized inflammatory response, which involves organ systems
remote from the locus of the initial infectious insult, involves the release of cytokines and the …
remote from the locus of the initial infectious insult, involves the release of cytokines and the …
Cardioprotective effect and influence on NOS expression of Montelukast sodium in rats
S Chen, G Jin, J Shan, M Zhang, Q Men… - Yao xue xue bao= Acta …, 2003 - europepmc.org
Aim To determine the protective effect and influence on NOS expression of Montelukast
sodium--a leukotriene antagonist on myocardial necrosis in rats. Methods Myocardial …
sodium--a leukotriene antagonist on myocardial necrosis in rats. Methods Myocardial …
CysLTR1 antagonism by montelukast can ameliorate diabetes-induced aortic and testicular inflammation
Aims Montelukast, a cysteinyl leukotriene receptor (CysLTR) 1 antagonist, is emerging as an
attractive strategy to curtail diabetic complications; however, its role in aortic and testicular …
attractive strategy to curtail diabetic complications; however, its role in aortic and testicular …
Celastrol attenuates symptoms of preeclampsia in rats by inhibiting matrix metalloproteinase-9
S Xiao, M Zhang, Z He, D Wang - European Journal of Pharmacology, 2018 - Elsevier
Preeclampsia is reported in pregnant women around the world and often causes
maternal/fetal mortality and morbidity. In the current study, we assessed the efficacy of …
maternal/fetal mortality and morbidity. In the current study, we assessed the efficacy of …
[HTML][HTML] Echinatin Inhibits Oxidative Stress and Inflammatory Processes in Trophoblast Cells by Inhibiting TLR4-MyD88-NF-κB Pathway in Preeclampsia
X Deng, H Chen, Y Zhang, F Xu, Q Zhou - Journal of Clinical …, 2024 - hindawi.com
Background. Preeclampsia (PE) is a common obstetric disorder hallmarked by impaired
trophoblast invasion and a skew toward an inflammatory immune response. Echinatin, a …
trophoblast invasion and a skew toward an inflammatory immune response. Echinatin, a …
Alkaloid leonurine exerts anti‐inflammatory effects via modulating MST1 expression in trophoblast cells
F Zong, Y Zhao - Immunity, Inflammation and Disease, 2021 - Wiley Online Library
Background Pre‐eclampsia (PE) is mainly attributed to the inflammation of trophoblast cells
in pregnant women, which results in damage to the maternal organs and growth retardation …
in pregnant women, which results in damage to the maternal organs and growth retardation …
[HTML][HTML] The effects of estradiol on inflammatory and endothelial dysfunction in rats with preeclampsia
ZH Lin, J Jin, XY Shan - International Journal of …, 2020 - spandidos-publications.com
Preeclampsia (PE), a hypertensive disorder during pregnancy, has adverse effects to both
the mother and the fetus. Maternal inflammatory and vascular endothelial dysfunction are …
the mother and the fetus. Maternal inflammatory and vascular endothelial dysfunction are …
Luteoloside attenuates neuroinflammation in focal cerebral ischemia in rats via regulation of the PPARγ/Nrf2/NF-κB signaling pathway
Q Li, Z Tian, M Wang, J Kou, C Wang, X Rong… - International …, 2019 - Elsevier
Luteoloside, a flavonoid compound, has been reported to have anti-inflammatory, anti-
oxidative, antibacterial, antiviral, anticancer, and cardioprotective effects, among others, but …
oxidative, antibacterial, antiviral, anticancer, and cardioprotective effects, among others, but …