Oxygen is vital for life as it is required for many different enzymatic reactions involved in
intermediate metabolism and xenobiotic biotransformation. Moreover, oxygen consumption …

Oxidative stress is a common pathogenetic mechanism contributing to initiation and
progression of hepatic damage in a variety of liver disorders. Cell damage occurs when …

The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Reactive oxygen species-(ROS-) induced oxidative stress has been implicated in various
forms of diseases. Excessive ROS generation depletes the endogenous antioxidants that …

Oxidative stress is a major pathogenetic event occurring in several liver disorders ranging
from metabolic to proliferative ones, and is a major cause of liver damage due to …

Redox state constitutes an important background of numerous liver disorders. The redox
state participates in the course of inflammatory, metabolic and proliferative liver diseases …

Oxidative stress is importantly involved in the pathophysiology of various liver diseases. The
redox state participates on the course of the inflammatory, metabolic and proliferative liver …

The increased production of derivatives of molecular oxygen and nitrogen in the form of
reactive oxygen species (ROS) and reactive nitrogen species (RNS) lead to molecular …

Chronic liver diseases are a public health issue, because of their high incidence and
prevalence, the important impact on the quality of life and high mortality rates. From a …

Liver disease is a highly prevalent disease that is one of the leading causes of death
worldwide. The continuous exposure of the liver to some factors such as viruses, alcohol, fat …