Background Invasion is an important early step of cancer metastasis that is not well
understood. Developing therapeutics to limit metastasis requires the identification and …

We recently identified the immunoglobulin-CAM CD155/PVR (the poliovirus receptor) as a
regulator of cancer invasiveness and glioma migration, but the mechanism through which …

Background/Aim: CD155 is expressed in many types of human cells and has diverse
functions. We herein evaluated the cli ni cal importance of CD155 in pancreatic cancer …

Originally identified as a molecular organizer of interacting proteins into tetraspanin-
enriched microdomains, the tetraspanin CD151 has now been shown to be involved in …

CD147 is highly expressed on many tumor cells; its role for tumor invasiveness and
metastasis has been deduced from its capacity to induce MMPs, ie, MMP-1,-2,-3, and-9 …

Pancreatic cancer is a lethal disease because of invasion and early metastasis. Although
CD133, a marker of cancer stem cells (CSCs) in a variety of solid tumors, has been studied …

The tetraspanin CD151 forms stoichiometric complexes with laminin-binding integrins (eg,
α3β1, α6β1, and α6β4) and regulates their ligand-binding and signaling functions. We have …

CD155 (poliovirus receptor) localizes in cell–matrix adhesions and cell–cell junctions, but its
role in the regulation of cell adhesion and cell motility has not been investigated. We …

CD146 is a cell adhesion molecule (CAM) that is primarily expressed at the intercellular
junction of endothelial cells. CD146 was originally identified as a tumor marker for …

Background CD155, an immunoglobulin-like adhesion molecule, plays an important role in
carcinoma such as cells migration, proliferation, metastasis, and tumor immune. The …