Long non-coding RNAs and microRNAs as crucial regulators in cardio-oncology
Cancer is one of the leading causes of morbidity and mortality worldwide. Significant
improvements in the modern era of anticancer therapeutic strategies have increased the …
improvements in the modern era of anticancer therapeutic strategies have increased the …
Non-coding RNAs in cancer therapy-induced cardiotoxicity: Mechanisms, biomarkers, and treatments
W Sun, J Xu, L Wang, Y Jiang, J Cui, X Su… - Frontiers in …, 2022 - frontiersin.org
As a result of ongoing breakthroughs in cancer therapy, cancer patients' survival rates have
grown considerably. However, cardiotoxicity has emerged as the most dangerous toxic side …
grown considerably. However, cardiotoxicity has emerged as the most dangerous toxic side …
Noncoding RNAs: potential regulators in cardioncology
Cancer is the leading cause of morbidity and mortality in the United States and globally.
Owing to improved early diagnosis and advances in oncological therapeutic options, the …
Owing to improved early diagnosis and advances in oncological therapeutic options, the …
Noncoding RNAs in doxorubicin-induced cardiotoxicity and their potential as biomarkers and therapeutic targets
H Fa, W Chang, X Zhang, D Xiao, J Wang - Acta Pharmacologica Sinica, 2021 - nature.com
Anthracyclines, such as doxorubicin (DOX), are well known for their high efficacy in treating
multiple cancers, but their clinical usage is limited due to their potential to induce fatal …
multiple cancers, but their clinical usage is limited due to their potential to induce fatal …
MicroRNAs in cancer treatment-induced cardiotoxicity
L Pellegrini, S Sileno, M D'Agostino, E Foglio… - Cancers, 2020 - mdpi.com
Cancer treatment has made significant progress in the cure of different types of tumors.
Nevertheless, its clinical use is limited by unwanted cardiotoxicity. Aside from the …
Nevertheless, its clinical use is limited by unwanted cardiotoxicity. Aside from the …
Circular RNAs at the intersection of cancer and heart disease: potential therapeutic targets in cardio-oncology
D Neufeldt, S Cushman, C Bär… - Cardiovascular …, 2023 - academic.oup.com
Considerable progress has been made in managing cancer; however, with these
advancements comes the discovery of previously unknown adverse events. In particular, the …
advancements comes the discovery of previously unknown adverse events. In particular, the …
Non‐coding RNAs: key players in cardiac disease
Molecular mechanisms underlying heart failure (HF) are only partly understood. Non‐coding
RNAs (ncRNAs) have been reported to control function and signalling routes in the …
RNAs (ncRNAs) have been reported to control function and signalling routes in the …
[HTML][HTML] A novel onco-cardiological mouse model of lung cancer-induced cardiac dysfunction and its application in identifying potential roles of tRNA-derived small …
Q Wu, S Zou, W Liu, M Liang, Y Chen, J Chang… - Biomedicine & …, 2023 - Elsevier
An increasing body of research suggests cancer-induced cardiovascular diseases, leading
to the appearance of an interdisciplinary study known as onco-cardiology. Lung cancer has …
to the appearance of an interdisciplinary study known as onco-cardiology. Lung cancer has …
Long noncoding RNA LINC00339 aggravates doxorubicin-induced cardiomyocyte apoptosis by targeting MiR-484
J Li, L Li, X Li, S Wu - Biochemical and biophysical research …, 2018 - Elsevier
Abnormally expressed long noncoding RNAs (lncRNAs) has been recognized as one of the
key source in cardiac diseases. However, the role of lncRNA in doxorubicin (DOX)-induced …
key source in cardiac diseases. However, the role of lncRNA in doxorubicin (DOX)-induced …
Breast cancer treatment and adverse cardiac events: what are the molecular mechanisms?
L Roca-Alonso, L Pellegrino, L Castellano, J Stebbing - Cardiology, 2012 - karger.com
Cardiotoxicity associated with breast cancer treatment is an important concern in the
oncology clinic. Different types of anti-cancer therapies have recorded high rates of cardiac …
oncology clinic. Different types of anti-cancer therapies have recorded high rates of cardiac …