Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …

Neurological illnesses, including cognitive impairment, memory decline and dementia, affect
over 50 million people worldwide, imposing a substantial burden on individuals and society …

It is now well-established that early life adversity (ELA) predisposes individuals to develop
several neuropsychiatric conditions, including anxiety disorders, and major depressive …

Comprehensive clinical studies show that adverse conditions in early life can severely
impact the developing brain and increase vulnerability to mood disorders later in life. During …

Exposure to early life stress (ELS), such as childhood abuse and neglect is a well
established major risk factor for developing psychiatric and behavioral disorders later in life …

Accumulating evidence suggests that adversities at critical periods in early life, both pre-and
postnatal, can lead to neuroendocrine perturbations, including hypothalamic-pituitary …

The impact that stressful encounters have upon long-lasting behavioural phenotypes is
varied. Whereas a significant proportion of the population will develop “stress-related” …

Exposure to early-life adversity (ELA) increases the risk for psychopathologies associated
with amygdala-prefrontal cortex (PFC) circuits. While sex differences in vulnerability have …

Early life stress (ELS) induces long-term phenotypic adaptations that contribute to increased
vulnerability to a host of neuropsychiatric disorders. Epigenetic mechanisms, including DNA …

Exposure to adversity and stress early in development yields vulnerability to mental
illnesses throughout the lifespan. Growing evidence suggests that this vulnerability has …