The role of the immune system in IBD-associated colorectal cancer: from pro to anti-tumorigenic mechanisms

S Frigerio, DA Lartey, GR D'haens… - International journal of …, 2021 - mdpi.com
Patients with inflammatory bowel disease (IBD) have increased incidence of colorectal
cancer (CRC). IBD-associated cancer follows a well-characterized sequence of intestinal …

The dual role of inflammation in colon carcinogenesis

G Monteleone, F Pallone, C Stolfi - International Journal of Molecular …, 2012 - mdpi.com
Chronic inflammation characterizing patients with inflammatory bowel disease (IBD)
represents a major risk factor for the development of colorectal cancer. Mechanisms …

Inflammatory bowel disease-associated colorectal cancer: translational risks from mechanisms to medicines

RJ Porter, MJ Arends… - Journal of Crohn's and …, 2021 - academic.oup.com
The cumulative impact of chronic inflammation in patients with inflammatory bowel diseases
predisposes to the development of inflammatory bowel disease-associated colorectal …

Inflammation and colorectal cancer: colitis-associated neoplasia

SI Grivennikov - Seminars in immunopathology, 2013 - Springer
Connection between inflammation and cancer is a rapidly developing field. Epidemiological
data suggests that inflammation along with distinct arms of host immune system plays a very …

Cytokines, IBD, and colitis-associated cancer

R Francescone, V Hou… - Inflammatory bowel …, 2015 - academic.oup.com
Inflammatory bowel diseases (IBDs) are debilitating conditions that result in intestinal
damage due to chronic inflammation. In addition, the perpetual state of inflammation …

Inflammatory bowel disease and risk of colorectal cancer: An overview from pathophysiology to pharmacological prevention

M Lucafò, D Curci, M Franzin, G Decorti… - Frontiers in …, 2021 - frontiersin.org
Increased risk of colorectal cancer (CRC) in inflammatory bowel disease (IBD) patients has
been attributed to long-standing chronic inflammation, with the contribution of genetic …

[HTML][HTML] Mechanisms of immune signaling in colitis-associated cancer

MJ Waldner, MF Neurath - Cellular and molecular gastroenterology and …, 2015 - Elsevier
The inflammatory bowel diseases ulcerative colitis and Crohn's disease are associated with
an increased risk for the development of colorectal cancer. During recent years, several …

Overcoming cancer risk in inflammatory bowel disease: new insights into preventive strategies and pathogenesis mechanisms including interactions of immune cells …

H Zhang, Y Shi, C Lin, C He, S Wang, Q Li… - Frontiers in …, 2024 - frontiersin.org
Inflammatory bowel disease (IBD), characterized primarily by gastrointestinal inflammation,
predominantly manifests as Crohn's disease (CD) and ulcerative colitis (UC). It is …

[HTML][HTML] Intestinal inflammation and colorectal cancer: a double-edged sword?

A Rizzo, F Pallone, G Monteleone… - World journal of …, 2011 - ncbi.nlm.nih.gov
Chronic inflammation is thought to be the leading cause of many human cancers including
colorectal cancer (CRC). Accordingly, epidemiologic and clinical studies indicate that …

The role of inflammation in the pathogenesis of colorectal cancer

BB McConnell, VW Yang - Current colorectal cancer reports, 2009 - Springer
Chronic inflammatory disorders are often associated with an increased risk of developing
cancer. A classic example of the connection between inflammation and cancer is the …