Construction of a prognostic model with CAFs for predicting the prognosis and immunotherapeutic response of lung squamous cell carcinoma
X Zhang, Q Xiao, C Zhang, Q Zhou… - Journal of Cellular and …, 2024 - Wiley Online Library
Lung squamous cell carcinoma (LUSC) is one of the subtypes of lung cancer (LC) that
contributes to approximately 25%–30% of its prevalence. Cancer‐associated fibroblasts …
contributes to approximately 25%–30% of its prevalence. Cancer‐associated fibroblasts …
[HTML][HTML] A novel signature predicts prognosis and immunotherapy in lung adenocarcinoma based on cancer-associated fibroblasts
Q Ren, P Zhang, H Lin, Y Feng, H Chi… - Frontiers in …, 2023 - frontiersin.org
Background Extensive research has established the significant correlations between cancer-
associated fibroblasts (CAFs) and various stages of cancer development, including initiation …
associated fibroblasts (CAFs) and various stages of cancer development, including initiation …
[HTML][HTML] Prognostic analysis of lung adenocarcinoma based on cancer-associated fibroblasts genes using scRNA-sequencing
H Zhang, Y Wang, K Wang, Y Ding, X Li, S Zhao… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Cancer-associated fibroblasts (CAFs) are an important component of the tumor
microenvironment (TME). CAFs can promote tumor occurrence and metastasis by promoting …
microenvironment (TME). CAFs can promote tumor occurrence and metastasis by promoting …
Integrative analyses of bulk and single-cell RNA-seq identified cancer-associated fibroblasts-related signature as a prognostic factor for immunotherapy in NSCLC
S Wang, G Fan, L Li, Y He, N Lou, T Xie, L Dai… - Cancer Immunology …, 2023 - Springer
An emerging view regarding cancer-associated fibroblast (CAF) is that it plays a critical role
in tumorigenesis and immunosuppression in the tumor microenvironment (TME), but the …
in tumorigenesis and immunosuppression in the tumor microenvironment (TME), but the …
[HTML][HTML] Development and validation of a novel fibroblast scoring model for lung adenocarcinoma
S Wei, X Gu, W Zhang - Frontiers in Oncology, 2022 - frontiersin.org
The interaction between cancer-associated fibroblasts (CAFs) and the tumor
microenvironment (TME) is a key factor for promoting tumor progression. In lung cancer, the …
microenvironment (TME) is a key factor for promoting tumor progression. In lung cancer, the …
[HTML][HTML] Machine learning identifies characteristics molecules of cancer associated fibroblasts significantly correlated with the prognosis, immunotherapy response …
Q Wang, X Zhang, K Du, X Wu, Y Zhou, D Chen… - Frontiers in …, 2022 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is a highly lethal disease with a dramatic pro-
fibrocytic response. Cancer-associated fibroblasts (CAFs) have been reported to play a key …
fibrocytic response. Cancer-associated fibroblasts (CAFs) have been reported to play a key …
[HTML][HTML] Identification of a cancer-associated fibroblast classifier for predicting prognosis and therapeutic response in lung squamous cell carcinoma
X Lai, G Fu, H Du, Z Xie, S Lin, Q Li, K Lin - Medicine, 2023 - journals.lww.com
Reliable prognostic gene signatures for cancer-associated fibroblasts (CAFs) in lung
squamous cell carcinoma (LUSC) are still lacking, and the underlying genetic principles …
squamous cell carcinoma (LUSC) are still lacking, and the underlying genetic principles …
Prognosis and immunotherapy significances of a cancer-associated fibroblasts-related gene signature in lung adenocarcinoma
Y Luo, S Zhang, H Xie, Q Su, S He… - Cellular and Molecular …, 2023 - mail.cellmolbiol.org
Cells associated with cancer (CAFs) contribute significantly to the stroma of a tumor
microenvironment (TME), which is related to the occurrence, treatment, and prognosis of …
microenvironment (TME), which is related to the occurrence, treatment, and prognosis of …
[HTML][HTML] Integrating single-cell and bulk RNA sequencing to develop a cancer-associated fibroblast-related signature for immune infiltration prediction and prognosis …
X Huang, H Xiao, Y Shi, S Ben - Journal of Thoracic Disease, 2023 - ncbi.nlm.nih.gov
Background An accumulating amount of studies are highlighting the impacts of cancer-
associated fibroblasts (CAFs) on the initiation, metastasis, invasion, and immune evasion of …
associated fibroblasts (CAFs) on the initiation, metastasis, invasion, and immune evasion of …
[HTML][HTML] Development and validation of a novel immune-related prognostic signature in lung squamous cell carcinoma patients
Abstract Lung Squamous Cell Carcinoma (LUSC) is an aggressive malignancy with limited
therapeutic options. The response to immune therapy is a determining factor for the …
therapeutic options. The response to immune therapy is a determining factor for the …