Acute brain trauma, lung injury, and pneumonia: more than just altered mental status and decreased airway protection
Traumatic brain injury (TBI) is a major cause of mortality and morbidity worldwide. Even
when patients survive the initial insult, there is significant morbidity and mortality secondary …
when patients survive the initial insult, there is significant morbidity and mortality secondary …
Traumatic brain injury in rats induces lung injury and systemic immune suppression
JD Vermeij, H Aslami, K Fluiter, JJ Roelofs… - Journal of …, 2013 - liebertpub.com
Traumatic brain injury (TBI) is frequently complicated by acute lung injury, which is predictive
for poor outcome. However, it is unclear whether lung injury develops independently or as a …
for poor outcome. However, it is unclear whether lung injury develops independently or as a …
Pathophysiology of acute lung injury in patients with acute brain injury: the triple-hit hypothesis
M Ziaka, A Exadaktylos - Critical Care, 2024 - Springer
It has been convincingly demonstrated in recent years that isolated acute brain injury (ABI)
may cause severe dysfunction of peripheral extracranial organs and systems. Of all potential …
may cause severe dysfunction of peripheral extracranial organs and systems. Of all potential …
Experimental models of hospital-acquired infections after traumatic brain injury: Challenges and opportunities
N Gandasasmita, J Li, DJ Loane… - Journal of …, 2024 - liebertpub.com
Patients hospitalized after a moderate or severe traumatic brain injury (TBI) are at increased
risk of nosocomial infections, including bacterial pneumonia and other upper respiratory …
risk of nosocomial infections, including bacterial pneumonia and other upper respiratory …
Brain–lung interactions and mechanical ventilation in patients with isolated brain injury
M Ziaka, A Exadaktylos - Critical care, 2021 - Springer
During the last decade, experimental and clinical studies have demonstrated that isolated
acute brain injury (ABI) may cause severe dysfunction of peripheral extracranial organs and …
acute brain injury (ABI) may cause severe dysfunction of peripheral extracranial organs and …
[HTML][HTML] Traumatic brain injury and peripheral immune suppression: primer and prospectus
Nosocomial infections are a common occurrence in patients following traumatic brain injury
(TBI) and are associated with an increased risk of mortality, longer length of hospital stay …
(TBI) and are associated with an increased risk of mortality, longer length of hospital stay …
Early or late bacterial lung infection increases mortality after traumatic brain injury in male mice and chronically impairs monocyte innate immune function
SJ Doran, RJ Henry, KA Shirey, JP Barrett… - Critical care …, 2020 - journals.lww.com
Objectives: Respiratory infections in the postacute phase of traumatic brain injury impede
optimal recovery and contribute substantially to overall morbidity and mortality. This study …
optimal recovery and contribute substantially to overall morbidity and mortality. This study …
The lung and the brain: a dangerous cross-talk
Brain or lung injury or both are frequent causes of admission to intensive care units and are
associated with high morbidity and mortality rates. Mechanical ventilation, which is …
associated with high morbidity and mortality rates. Mechanical ventilation, which is …
Bidirectional brain-systemic interactions and outcomes after TBI
Traumatic brain injury (TBI) is a debilitating disorder associated with chronic progressive
neurodegeneration and long-term neurological decline. Importantly, there is now substantial …
neurodegeneration and long-term neurological decline. Importantly, there is now substantial …
ARDS associated acute brain injury: from the lung to the brain
M Ziaka, A Exadaktylos - European journal of medical research, 2022 - Springer
A complex interrelation between lung and brain in patients with acute lung injury (ALI) has
been established by experimental and clinical studies during the last decades. Although …
been established by experimental and clinical studies during the last decades. Although …
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