[HTML][HTML] Omics and male infertility: highlighting the application of transcriptomic data
TS Omolaoye, VA Omolaoye, RK Kandasamy… - Life, 2022 - mdpi.com
Male infertility is a multifaceted disorder affecting approximately 50% of male partners in
infertile couples. Over the years, male infertility has been diagnosed mainly through semen …
infertile couples. Over the years, male infertility has been diagnosed mainly through semen …
[HTML][HTML] Towards a multi-omics of male infertility
AO Wagner, A Turk, T Kunej - The world journal of men's health, 2023 - ncbi.nlm.nih.gov
Infertility is a common problem affecting one in six couples and in 30% of infertile couples,
the male factor is a major cause. A large number of genes are involved in spermatogenesis …
the male factor is a major cause. A large number of genes are involved in spermatogenesis …
[HTML][HTML] Transcriptomic signatures for human male infertility
Introduction: Male infertility is a common, complex disorder. A better understanding of
pathogenesis and etiology is needed for timely diagnosis and treatment. The aim of this …
pathogenesis and etiology is needed for timely diagnosis and treatment. The aim of this …
[HTML][HTML] Future diagnostics in male infertility: Genomics, epigenetics, metabolomics and proteomics
SC Krzastek, RP Smith, JR Kovac - Translational Andrology and …, 2020 - ncbi.nlm.nih.gov
A male factor is involved in 50% of couples with infertility. Unfortunately, the etiology of male
factor infertility remains classified as idiopathic in nearly 50% of cases. The semen analysis …
factor infertility remains classified as idiopathic in nearly 50% of cases. The semen analysis …
[HTML][HTML] Using publicly available transcriptomic data to identify mechanistic and diagnostic biomarkers in azoospermia and overall male infertility
Azoospermia, which is the absence of spermatozoa in an ejaculate occurring due to defects
in sperm production, or the obstruction of the reproductive tract, affects about 1% of all men …
in sperm production, or the obstruction of the reproductive tract, affects about 1% of all men …
[HTML][HTML] The use of genomics, proteomics, and metabolomics in identifying biomarkers of male infertility
JR Kovac, AW Pastuszak, DJ Lamb - Fertility and sterility, 2013 - Elsevier
Although male factors account for approximately 50% of all infertility, the mechanisms
underlying their origin are unknown. Currently, clinicians rely primarily on semen analyses …
underlying their origin are unknown. Currently, clinicians rely primarily on semen analyses …
[PDF][PDF] Multi-omics and male infertility: status, integration and future prospects
Within the cell, gene expression analysis is the key to gain information about different
cellular and physiological events. The multifaceted route of fertilization is a combination of …
cellular and physiological events. The multifaceted route of fertilization is a combination of …
Recent insights on the significance of transcriptomic and metabolomic analysis of male factor infertility
Infertility is a worldwide reproductive health problem which affects approximately 15% of
couples, with male factor infertility dominating nearly 50% of the affected population. The …
couples, with male factor infertility dominating nearly 50% of the affected population. The …
[HTML][HTML] A systematic review identifying fertility biomarkers in semen: a clinical approach through omics to diagnose male infertility
Objective To identify the most robust molecular biomarkers in sperm and seminal plasma for
the diagnosis of male infertility, and to evaluate their clinical use. Design Systematic review …
the diagnosis of male infertility, and to evaluate their clinical use. Design Systematic review …
Human male infertility: a complex multifactorial phenotype
K Singh, D Jaiswal - Reproductive sciences, 2011 - journals.sagepub.com
Infertility is a major reproductive health problem affecting 10% to 15% of couples, with
approximately equal contributions. Spermatogenesis is a dynamic and multistep process of …
approximately equal contributions. Spermatogenesis is a dynamic and multistep process of …