Methods of tissue decellularization used for preparation of biologic scaffolds and in vivo relevance

TJ Keane, IT Swinehart, SF Badylak - Methods, 2015 - Elsevier
Biologic scaffolds composed of extracellular matrix (ECM) are widely used in both preclinical
animal studies and in many clinical applications to repair and reconstruct tissues. Recently …

Decellularization of tissues and organs

TW Gilbert, TL Sellaro, SF Badylak - Biomaterials, 2006 - Elsevier
Decellularized tissues and organs have been successfully used in a variety of tissue
engineering/regenerative medicine applications, and the decellularization methods used …

An overview of tissue and whole organ decellularization processes

PM Crapo, TW Gilbert, SF Badylak - Biomaterials, 2011 - Elsevier
Biologic scaffold materials composed of extracellular matrix (ECM) are typically derived by
processes that involve decellularization of tissues or organs. Preservation of the complex …

Tissue and organ decellularization in regenerative medicine

R Guruswamy Damodaran… - Biotechnology progress, 2018 - Wiley Online Library
The advancement and improvement in decellularization methods can be attributed to the
increasing demand for tissues and organs for transplantation. Decellularized tissues and …

[HTML][HTML] Decellularized extracellular matrix mediates tissue construction and regeneration

C Liu, M Pei, Q Li, Y Zhang - Frontiers of medicine, 2022 - Springer
Contributing to organ formation and tissue regeneration, extracellular matrix (ECM)
constituents provide tissue with three-dimensional (3D) structural integrity and cellular …

Decellularization strategies for regenerative medicine: from processing techniques to applications

A Gilpin, Y Yang - BioMed research international, 2017 - Wiley Online Library
As the gap between donors and patients in need of an organ transplant continues to widen,
research in regenerative medicine seeks to provide alternative strategies for treatment. One …

Extracellular matrix-based materials for regenerative medicine

GS Hussey, JL Dziki, SF Badylak - Nature Reviews Materials, 2018 - nature.com
In tissue engineering and regenerative medicine, a biomaterial provides mechanical support
and biochemical signals to encourage cell attachment and modulate cell behaviour …

Strategies for tissue and organ decellularization

TW Gilbert - Journal of cellular biochemistry, 2012 - Wiley Online Library
Decellularized tissues have been successfully used in a variety of tissue engineering/
regenerative medicine applications, and more recently decellularized organs have been …

Consequences of ineffective decellularization of biologic scaffolds on the host response

TJ Keane, R Londono, NJ Turner, SF Badylak - Biomaterials, 2012 - Elsevier
Biologic scaffold materials composed of extracellular matrix (ECM) are routinely used for a
variety of clinical applications. Despite known variations in tissue remodeling outcomes …

[HTML][HTML] Preparation and use of decellularized extracellular matrix for tissue engineering

AD McInnes, MAJ Moser, X Chen - Journal of functional biomaterials, 2022 - mdpi.com
The multidisciplinary fields of tissue engineering and regenerative medicine have the
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …