The aim of this study was to examine the potential of platelet-derived growth factor (PDGF)-
coated decellularized meniscus scaffold in mediating integrative healing of meniscus tears …

Few therapeutic options exist for meniscus repair after injury. Local delivery of growth factors
may stimulate repair and create a favorable environment for engineered replacement …

BACKGROUND: Meniscus tissue engineering has provided a great potential treatment for
meniscal injuries. However, few scaffolds in meniscus tissue engineering have matched the …

Meniscus deficiency, the most common and refractory disease in human knee joints, often
progresses to osteoarthritis (OA) due to abnormal biomechanical distribution and articular …

Meniscal injuries, particularly in the avascular zone, have a low propensity for healing and
are associated with the development of osteoarthritis. Current meniscal repair techniques …

Decellularized scaffolds composed of extracellular matrix (ECM) hold promise for repair and
regeneration of the meniscus, given the potential for ECM-based biomaterials to aid in stem …

The inability of the avascular region of the meniscus to regenerate has led to the use of
tissue engineering to treat meniscal injuries. The aim of this study was to evaluate the ability …

Meniscal tears have a poor healing capacity, and damage to the meniscus is associated
with significant pain, disability, and progressive degenerative changes in the knee joint that …

Purpose: Meniscal injury and loss of meniscus tissue lead to osteoarthritis development.
Therefore, novel biologic strategies are needed to enhance meniscus tissue repair. The …

Electrospinning is an attractive method of fabricating nanofibers that replicate the
ultrastructure of the human meniscus. However, it is challenging to approximate the …