Large bone defect regeneration has always been recognized as a challenging clinical
problem due to the difficulty of revascularization. Conventional treatments exhibit certain …

Abstract 3D printed scaffolds hold promising perspective for bone tissue regeneration.
Inspired by process of bone development stage, 3D printed scaffolds with rapid internal …

Vascularization is a fundamental prerequisite for large bone construct development and
remains one of the main challenges of bone tissue engineering. Our current study presents …

Abstract 3D printing technology is an emerging technology. It constructs solid bodies by
stacking materials layer by layer, and can quickly and accurately prepare bone tissue …

Bone defect caused by specific diseases or medications is very common. Autologous bone,
allogeneic bone or xenogeneic bone transplantation is commonly used in clinical practice …

The development of sufficient vascular networks is crucial for the successful fabrication of
tissue constructs for regenerative medicine, as vascularization is essential to perform the …

A functional vascular supply is a key component of any large-scale tissue, providing support
for the metabolic needs of tissue-remodeling cells. Although well-studied strategies exist to …

Over the last decades, the number of work accidents associated with bone fractures has
increased leading to a growing concern worldwide. Currently, autografts, allografts, and …

The design of scaffolds that could adjust and adapt greatly to bone defects is a significant
challenge to bone tissue engineering. Recently, 3D printing technology emerged as a …

The suffering from organ dysfunction due to damaged or diseased tissue/bone has been
globally on the rise. Current treatment strategies for non-union bone defects include: the use …