A causal atlas on comorbidities in idiopathic pulmonary fibrosis: a bidirectional Mendelian randomization study
Background Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease with a high burden of
both pulmonary and extrapulmonary comorbidities. Research Question Do these …
both pulmonary and extrapulmonary comorbidities. Research Question Do these …
[HTML][HTML] Endocrine and metabolic factors and the risk of idiopathic pulmonary fibrosis: a mendelian randomization study
Y Jiang, R Chen, S Xu, Y Ding, M Zhang… - Frontiers in …, 2024 - frontiersin.org
Background: Previous observational studies have investigated the association between
endocrine and metabolic factors and idiopathic pulmonary fibrosis (IPF), yet have produced …
endocrine and metabolic factors and idiopathic pulmonary fibrosis (IPF), yet have produced …
Appraising the causal role of smoking in idiopathic pulmonary fibrosis: a Mendelian randomization study
J Zhu, D Zhou, M Yu, Y Li - thorax, 2024 - thorax.bmj.com
Smoking has been considered a risk factor for idiopathic pulmonary fibrosis (IPF) in
observational studies. To assess whether smoking plays a causal role in IPF, we performed …
observational studies. To assess whether smoking plays a causal role in IPF, we performed …
Genome-wide association study of susceptibility to idiopathic pulmonary fibrosis
Rationale: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease characterized by
scarring of the lung that is believed to result from an atypical response to injury of the …
scarring of the lung that is believed to result from an atypical response to injury of the …
Genome-wide association study across five cohorts identifies five novel loci associated with idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic lung condition with poor survival times. We
previously published a genome-wide meta-analysis of IPF risk across three studies with …
previously published a genome-wide meta-analysis of IPF risk across three studies with …
Mendelian randomisation highlights hypothyroidism as a causal determinant of idiopathic pulmonary fibrosis
Y Zhang, M Zhao, P Guo, Y Wang, L Liu, J Zhao… - …, 2021 - thelancet.com
Background Although the association between hypothyroidism and idiopathic pulmonary
fibrosis (IPF) is found in observational studies, it remains uncertain whether hypothyroidism …
fibrosis (IPF) is found in observational studies, it remains uncertain whether hypothyroidism …
Diabetes mellitus and idiopathic pulmonary fibrosis: a Mendelian randomization study
Q Kang, J Ren, J Cong, W Yu - BMC Pulmonary Medicine, 2024 - Springer
Background The question as to whether or not diabetes mellitus increases the risk of
idiopathic pulmonary fibrosis (IPF) remains controversial. This study aimed to investigate the …
idiopathic pulmonary fibrosis (IPF) remains controversial. This study aimed to investigate the …
Idiopathic pulmonary fibrosis is associated with common genetic variants and limited rare variants
AL Peljto, RZ Blumhagen, AD Walts… - American journal of …, 2023 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is a rare, irreversible, and progressive disease
of the lungs. Common genetic variants, in addition to nongenetic factors, have been …
of the lungs. Common genetic variants, in addition to nongenetic factors, have been …
Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study
Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with
high mortality, uncertain cause, and few treatment options. Studies have identified a …
high mortality, uncertain cause, and few treatment options. Studies have identified a …
Integrative analyses for the identification of idiopathic pulmonary fibrosis-associated genes and shared loci with other diseases
Background Although genome-wide association studies (GWAS) have identified many
genomic regions associated with idiopathic pulmonary fibrosis (IPF), the causal genes and …
genomic regions associated with idiopathic pulmonary fibrosis (IPF), the causal genes and …