Accumulating evidence has linked G-quadruplex structures to a number of biological
processes in vivo, including DNA replication, transcription, and genomic maintenance …

G-quadruplexes are non-canonical nucleic acid structures formed by guanine-rich DNA or
RNA sequences. In recent decades, an increasing number of evidences have suggested …

Guanine-rich nucleic acids can fold into non-canonical DNA secondary structures called G-
quadruplexes. The formation of these structures can interfere with the biology that is crucial …

Mounting evidence supports the presence of biologically relevant G‐quadruplexes in single‐
cell organisms, but the existence of endogenous G‐quadruplex structures in mammalian …

G-quadruplexes are nucleic acids secondary structures that can be formed in guanine-rich
sequences. More than 30 years ago, their formation was first observed in telomeric DNA …

Background Direct detection of G-quadruplexes in human cells has become an important
issue due to the vital role of G-quadruplex related to biological functions. Despite several …

G-quadruplexes have gained prominence over the past two decades for their role in gene
regulation, control of anti-tumour activity and ageing. The physiological relevance and …

G-quadruplexes are non-Watson-Crick four-stranded nucleic acid structures. Recent
evidence points toward their existence in vivo and their implication in various biological …

Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that
involve G-quartets linked by loop nucleotides. The structural and topological diversity of G …

Biophysical and biochemical investigations provide compelling evidence connecting the
four-stranded G-quadruplex (GQ) structure with its role in regulating multiple cellular …