Nickel (Ni) is a worldwide pollutant and contaminant that humans are exposed to through
various avenues resulting in multiple toxic responses—most alarming is its clear …

Nickel (Ni) metal and Ni compounds are widely used in applications like stainless steel,
alloys, and batteries. Nickel is a naturally occurring element in water, soil, air, and living …

Micron-sized particles of poorly soluble nickel compounds, but not metallic nickel, are
established human and rodent carcinogens. In contrast, little is known about the toxic effects …

The intraceliular fate of particulate crystalline αNiS, an inducer of neoplastic transformation
which is readily phagocytized by cultured cells, was compared with that of particulate …

Alveolar macrophages collected by pulmonary lavage from male Fischer-344 rats at
intervals (1–72 hr) after NiCl2 injection (62–500 μmol/kg, sc) were tested by several …

Metallic nanoparticles (NPs) have been widely applied in the field of nanomedicine. A
comprehensive understanding of their pharmacokinetics is crucial for proper risk …

As one of the most promising and effective delivery systems for targeted controlled-release
drugs, nanocarriers (NCs) have been widely studied. Although the development of …

The mechanism (s) of nanoparticle–cell interactions are still not understood. At present there
is little knowledge of the relevant length‐and timescales for nanoparticle intracellular entry …

Background The toxicokinetics of nanomaterials are an important factor in toxicity, which
may be affected by slow clearance and/or distribution in the body. Methods Four types of …

Metal nanoparticles (NPs) are frequently encountered in daily life, and concerns have been
raised about their toxicity and safety. Among which, they naturally accumulate in the liver …