Objective The purpose of this retrospective cross-sectional study was to investigate whether
changes in white matter integrity are related to slower processing speed in sickle cell …

Objective: This study was conducted to determine the relationship of frontal lobe cortical
thickness and basal ganglia volumes to measures of cognition in adults with sickle cell …

Research in sickle cell anemia (SCA) has used, with limited race-matched control data,
binary categorization of patients according to the presence or absence of silent cerebral …

Objective To determine the patient-and tissue-based relationships between cerebral
hemodynamic and oxygen metabolic stress, microstructural injury, and infarct location in …

Children diagnosed with sickle cell disease (SCD) have an increased risk of stroke, often
associated with white matter damage and neurocognitive morbidity. Growing evidence …

Background and Purpose: Individuals with sickle cell anemia experience cognitive deficits,
even in the absence of cerebral infarcts or strokes. This study tested the hypothesis that …

Sickle cell disease (SCD) is a life-threatening genetic condition. Patients suffer from chronic
systemic and cerebral vascular disease that leads to early and cumulative neurological …

Severe chronic anemia is an independent predictor of overt stroke, white matter damage,
and cognitive dysfunction in the elderly. Severe anemia also predisposes to white matter …

Background and Purpose—Sickle cell anemia is associated with compromised oxygen-
carrying capability of hemoglobin and a high incidence of overt and silent stroke. However …

Background Although neurocognitive deficits in children with sickle cell disease (SCD) have
been well documented, the etiology of these deficits has not been completely clarified. The …