Candidate drugs against SARS-CoV-2 and COVID-19

DL McKee, A Sternberg, U Stange, S Laufer… - Pharmacological …, 2020 - Elsevier
Outbreak and pandemic of coronavirus SARS-CoV-2 in 2019/2020 will challenge global
health for the future. Because a vaccine against the virus will not be available in the near …

Strategies for targeting sars cov-2: Small molecule inhibitors—The current status

NM Beeraka, SP Sadhu… - Frontiers in …, 2020 - frontiersin.org
Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2) induced Coronavirus
Disease-19 (COVID-19) cases have been increasing at an alarming rate (7.4 million positive …

Inhibition of SARS-CoV-2 entry through the ACE2/TMPRSS2 pathway: a promising approach for uncovering early COVID-19 drug therapies

G Ragia, VG Manolopoulos - European journal of clinical pharmacology, 2020 - Springer
Aim The COVID-19 pandemic caused by infection with the novel coronavirus SARS-CoV-2
is urging the scientific community worldwide to intense efforts for identifying and developing …

After the hurricane: Anti-COVID-19 drugs development, molecular mechanisms of action and future perspectives

HO Khalifa, YM Al Ramahi - International Journal of Molecular Sciences, 2024 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a new coronavirus in
the Coronaviridae family. The COVID-19 pandemic, caused by SARS-CoV-2, has …

[HTML][HTML] An overview of the safety, clinical application and antiviral research of the COVID-19 therapeutics

D Wang, Z Li, Y Liu - Journal of infection and public health, 2020 - Elsevier
Since a novel coronavirus pneumonia outbreak in late December 2019, coronavirus disease-
19 (COVID-19) epidemic has gradually spread worldwide, becoming a major public health …

The rationale for potential pharmacotherapy of COVID-19

M Saber-Ayad, MA Saleh, E Abu-Gharbieh - Pharmaceuticals, 2020 - mdpi.com
On 11 March 2020, the coronavirus disease (COVID-19) was defined by the World Health
Organization as a pandemic. Severe acute respiratory syndrome-2 (SARS-CoV-2) is the …

Potential therapeutic targets and promising drugs for combating SARS‐CoV‐2

H Zhou, Y Fang, T Xu, WJ Ni, AZ Shen… - British Journal of …, 2020 - Wiley Online Library
As of April 9, 2020, a novel coronavirus (SARS‐CoV‐2) had caused 89,931 deaths and
1,503,900 confirmed cases worldwide, which indicates an increasingly severe and …

Natural products and phytochemicals as potential anti‐SARS‐CoV‐2 drugs

M Merarchi, N Dudha, BC Das… - Phytotherapy Research, 2021 - Wiley Online Library
The current pandemic responsible for the crippling of the health care system is caused by
the novel SARS‐CoV‐2 in 2019 and leading to coronavirus disease 2019 (COVID‐19). The …

An update on current therapeutic drugs treating COVID-19

R Wu, L Wang, HCD Kuo, A Shannar, R Peter… - Current pharmacology …, 2020 - Springer
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has presented unprecedented …

Discovering drugs to treat coronavirus disease 2019 (COVID-19)

L Dong, S Hu, J Gao - Drug discoveries & therapeutics, 2020 - jstage.jst.go.jp
The SARS-CoV-2 virus emerged in December 2019 and then spread rapidly worldwide,
particularly to China, Japan, and South Korea. Scientists are endeavoring to find antivirals …