The immunopathology of complement proteins and innate immunity in autoimmune disease
F Defendi, NM Thielens, G Clavarino… - Clinical Reviews in …, 2020 - Springer
The complement is a powerful cascade of the innate immunity and also acts as a bridge
between innate and acquired immune defence. Complement activation can occur via three …
between innate and acquired immune defence. Complement activation can occur via three …
Complement and autoimmunity
E Ballanti, C Perricone, E Greco, M Ballanti… - Immunologic …, 2013 - Springer
The complement system is a component of the innate immune system. Its main function was
initially believed to be limited to the recognition and elimination of pathogens through direct …
initially believed to be limited to the recognition and elimination of pathogens through direct …
Role of complement in innate immunity and host defense
LA Trouw, MR Daha - Immunology letters, 2011 - Elsevier
The complement system is an important part of the innate immune defense. Next to its role
as an effector mechanism of the innate immune system, complement also plays a major role …
as an effector mechanism of the innate immune system, complement also plays a major role …
Autoantibodies against complement components and functional consequences
MA Dragon-Durey, C Blanc, MC Marinozzi… - Molecular …, 2013 - Elsevier
The complement system represents a major component of our innate immune defense.
Although the physiological contribution of the complement system is beneficial, it can cause …
Although the physiological contribution of the complement system is beneficial, it can cause …
Complement in autoimmune diseases
The complement system is an ancient and evolutionary conserved element of the innate
immune mechanism. It comprises of more than 20 serum proteins most of which are …
immune mechanism. It comprises of more than 20 serum proteins most of which are …
The complement system as a therapeutic target in autoimmunity
VM Holers - Clinical Immunology, 2003 - Elsevier
The complement system is a central component of innate immunity [1] and is functionally
linked to both the activation and regulatory as well as the effector arms of adaptive immunity …
linked to both the activation and regulatory as well as the effector arms of adaptive immunity …
[HTML][HTML] Complement as a regulator of adaptive immunity
The complement system is an ancient and evolutionarily conserved effector system
comprising in mammals over 50 circulating and membrane bound proteins. Complement …
comprising in mammals over 50 circulating and membrane bound proteins. Complement …
Autoantibodies to complement components
LA Trouw, A Roos, MR Daha - Molecular immunology, 2001 - Elsevier
The complement system is a major component of innate immunity. Under normal conditions
the contribution of the complement system is beneficial, but when inappropriately activated it …
the contribution of the complement system is beneficial, but when inappropriately activated it …
[HTML][HTML] Complement as a therapeutic target in systemic autoimmune diseases
M Galindo-Izquierdo, JL Pablos Alvarez - Cells, 2021 - mdpi.com
The complement system (CS) includes more than 50 proteins and its main function is to
recognize and protect against foreign or damaged molecular components. Other …
recognize and protect against foreign or damaged molecular components. Other …
The role of complement in inflammatory diseases from behind the scenes into the spotlight
MM Markiewski, JD Lambris - The American journal of pathology, 2007 - Elsevier
Our understanding of the biology of the complement system has undergone a drastic
metamorphosis since its original discovery. This system, which was traditionally primarily …
metamorphosis since its original discovery. This system, which was traditionally primarily …