[HTML][HTML] Metabolomic-based clinical studies and murine models for acute pancreatitis disease: A review
Acute pancreatitis (AP) is one of the most common gastroenterological disorders requiring
hospitalization and is associated with substantial morbidity and mortality. Metabolomics …
hospitalization and is associated with substantial morbidity and mortality. Metabolomics …
GC-MS based metabolomics strategy to distinguish three types of acute pancreatitis
J Huang, D He, L Chen, C Dong, S Zhang, Y Qin, R Yu… - Pancreatology, 2019 - Elsevier
Acute pancreatitis (AP) is a progressive systemic inflammatory response with high morbidity
and high mortality, which is mainly caused by alcohol, bulimia, gallstones and …
and high mortality, which is mainly caused by alcohol, bulimia, gallstones and …
Identification of potential diagnostic biomarkers of acute pancreatitis by serum metabolomic profiles
H Xiao, J Huang, X Zhang, R Ahmed, Q Xie, B Li, Y Zhu… - Pancreatology, 2017 - Elsevier
Acute pancreatitis (AP) is defined as an acute inflammation of pancreas that may cause
damage to other tissues and organs depending upon the severity of symptoms. The …
damage to other tissues and organs depending upon the severity of symptoms. The …
Metabolomic analysis to discover candidate therapeutic agents against acute pancreatitis
A Sakai, S Nishiumi, Y Shiomi, T Kobayashi… - Archives of biochemistry …, 2012 - Elsevier
Novel and effective drugs against acute pancreatitis are required. Therefore, we examined
the changes in the metabolite levels in the serum and pancreatic tissue of mice with cerulein …
the changes in the metabolite levels in the serum and pancreatic tissue of mice with cerulein …
Clinical application of metabolomics in pancreatic diseases: A mini-review
W Gu, Z Tong - Laboratory Medicine, 2020 - academic.oup.com
Metabolomics is a powerful new analytical method to describe the set of metabolites within
cellular tissue and bodily fluids. Metabolomics can uncover detailed information about …
cellular tissue and bodily fluids. Metabolomics can uncover detailed information about …
Multi-dimensional metabolomic profiling reveals dysregulated ornithine metabolism hallmarks associated with a severe acute pancreatitis phenotype
J Yang, N Shi, S Wang, M Wang, Y Huang, Y Wang… - Translational …, 2024 - Elsevier
To reveal dysregulated metabolism hallmark that was associated with a severe acute
pancreatitis (SAP) phenotype. In this study, LC-MS/MS-based targeted metabolomics was …
pancreatitis (SAP) phenotype. In this study, LC-MS/MS-based targeted metabolomics was …
Temporal metabolic trajectory analyzed by LC-MS/MS based targeted metabolomics in acute pancreatitis pathogenesis and Chaiqin Chengqi decoction therapy
Y Huang, Y Wen, R Wang, L Hu, J Yang, J Yang, Q Pu… - Phytomedicine, 2022 - Elsevier
Background Acute pancreatitis (AP) is an inflammatory disorder of pancreas that lacks
effective specific drugs as well as gold standard laboratory tests for diagnosis and severity …
effective specific drugs as well as gold standard laboratory tests for diagnosis and severity …
[HTML][HTML] 1HNMR-based metabolomic profile of rats with experimental acute pancreatitis
J Li, X Zhao, Y Liu, X Peng, S Zhu, H Guo, YL Liu… - BMC …, 2014 - Springer
Background Acute pancreatitis (AP) is a common inflammatory disease of the pancreas
accompanied by serious metabolic disturbances. Nevertheless, the specific metabolic …
accompanied by serious metabolic disturbances. Nevertheless, the specific metabolic …
Multi-dimensional, comprehensive sample extraction combined with LC-GC/MS analysis for complex biological samples: application in the metabolomics study of …
Q Yang, J Sun, YQ Chen - RSC advances, 2016 - pubs.rsc.org
An analytical strategy employing multi-dimensional sample extraction together with optimal
analytical platforms was established. The proposed workflow was based on the fact that …
analytical platforms was established. The proposed workflow was based on the fact that …
Biomarkers of acute and chronic pancreatitis
BS Kaphalia - Biomarkers in Toxicology, 2014 - Elsevier
Pancreatitis and pancreatic cancers are very serious diseases with very poor prognosis, and
many patients die before even reaching the clinical stage. Therefore, identification of reliable …
many patients die before even reaching the clinical stage. Therefore, identification of reliable …
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