Thymoquinone counteracts oxidative and inflammatory machinery in carrageenan-induced murine paw edema model

HHA Hijazy, N Dahran, HA Althagafi, F Alharthi… - … Science and Pollution …, 2023 - Springer
Thymoquinone (TQ) is an active constituent in Nigella sativa (black cumin) and is
extensively reported for its distinguished antioxidant and anti-inflammatory bioactivities …

The ameliorative effect of thymoquinone on vincristine-induced peripheral neuropathy in mice by modulating cellular oxidative stress and cytokine

SK Alenezi - Life, 2022 - mdpi.com
Thymoquinone (TQ), an active constituent of Nigella sativa, has been reported to exert a
broad spectrum of pharmacological effects, including neuroprotective, anticancer, anti …

[HTML][HTML] Anti-inflammatory effects of thymoquinone and its protective effects against several diseases

Z Kohandel, T Farkhondeh, M Aschner… - Biomedicine & …, 2021 - Elsevier
Abstract Thymoquinone (TQ, 2-methyl-5-isopropyl-1, 4-benzoquinone), a monoterpene
molecule present in Nigella sativa L., has an anti-inflammatory, anti-oxidant, and anti …

Protocatechuic acid counteracts oxidative stress and inflammation in carrageenan-induced paw edema in mice

AJA Albarakati - Environmental Science and Pollution Research, 2022 - Springer
Protocatechuic acid (PCA), a phenolic compound found in teas, fruits, and vegetables, is
widely recognized with its antioxidant and anti-inflammatory activities. Here, we verified the …

Anti‐inflammatory effects of thymoquinone in LPS‐stimulated BV‐2 murine microglia cells (730.2)

E Taka, E Mazzio, C Goodman, R Reeams… - The FASEB …, 2014 - Wiley Online Library
Thymoquinone (TQ) is one the main pharmacologically active constituents of the black
cumin seeds (Nigella sativa) believed to be responsible for therapeutic effects on chronic …

Thymoquinone, extract from Nigella sativa seeds, protects human skin keratinocytes against UVA-irradiated oxidative stress, inflammation and mitochondrial …

J Liang, L Lian, X Wang, L Li - Molecular Immunology, 2021 - Elsevier
Ultraviolet A (UVA) irradiation caused skin keratinocytes to accumulate reactive oxygen
species (ROS) leading to the skin injury. Thymoquinone (TQ) was identified as the …

Thymoquinone inhibits phorbol ester-induced activation of NF-κB and expression of COX-2, and induces expression of cytoprotective enzymes in mouse skin in vivo

JK Kundu, L Liu, JW Shin, YJ Surh - Biochemical and biophysical research …, 2013 - Elsevier
Thymoquinone (TQ), the active ingredient of Nigella sativa, has been reported to possess
anti-inflammatory and chemopreventive properties. The present study was aimed at …

[HTML][HTML] Thymoquinone reduces spinal cord injury by inhibiting inflammatory response, oxidative stress and apoptosis via PPAR‑γ and PI3K/Akt pathways

Y Chen, B Wang, H Zhao - … and therapeutic medicine, 2018 - spandidos-publications.com
The present study used a mild contusion injury in rat spinal cord to determine that
thymoquinone reduces inflammatory response, oxidative stress and apoptosis in a spinal …

Nigella sativa, active principle thymoquinone, alleviates palmitate-induced cytotoxicity, inflammation and bioenergetic disruptions in macrophages: An invitro study …

R Othman, A Aggour, E Elmorsy, MS Fawzy - Toxicon, 2024 - Elsevier
Thymoquinone (TQ) is one of the main phytochemical bioactive ingredients in Nigella sativa,
with reported immunity-boosting properties. The current study evaluated the anti …

Protective Effects of Thymoquinone, an Active Compound of Nigella sativa, on Rats with Benzo(a)pyrene-Induced Lung Injury through Regulation of Oxidative Stress …

MA Alzohairy, AA Khan, MA Alsahli, SA Almatroodi… - Molecules, 2021 - mdpi.com
Benzopyrene [B (a) P] is a well-recognized environmental carcinogen, which promotes
oxidative stress, inflammation, and other metabolic complications. In the current study, the …