Alzheimer's disease (AD) is one of the major neurodegenerative diseases that deteriorates
cognitive functions and primarily affects associated brain regions involved in learning and …

Alzheimer's disease (AD) is the most common cause of dementia in elderly people.
Research focused on identifying compounds that restore cognition and memory in AD …

Cognitive dysfunction is one of the most typical characteristics in various neurodegenerative
diseases such as Alzheimer's disease and Parkinson's disease (advanced stage). Although …

Data from post-mortem brain, cerebrospinal fluid and serotonin (5-HT) synapse studies
indicate serious impairment of the serotoninergic system in patients with Alzheimer's …

Mounting evidence accumulated over the past few years indicates that the neurotransmitter
serotonin plays a significant role in cognition. As a drug target, serotonin receptors have …

Symptoms of cognitive dysfunction like memory loss, poor concentration, impaired learning
and executive functions are characteristic features of both schizophrenia and Alzheimer's …

Serotonin (5-HT) neuron and neurotransmitter loss in normal aging and neuropsychiatric
diseases of late life may contribute to behavioral changes commonly observed in the elderly …

Abstract Behavioral and Psychological Symptoms of Dementia (BPSD), present in almost
90% of patients with Alzheimer's Disease (AD), cause extensive impairment leading to …

The indolamine, serotonin (5-hydroxytryptamine-5-HT) was identified and initially
characterized around the middle of the twentieth century and it is now known to participate in …

Abstract Serotonin, or 5-hydroxytryptamine (5-HT), is found to be involved in many
physiological or pathophysiological processes including cognitive function. Seven distinct …